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EXPERIMENTAL STUDIES OF SURFACE-DRIVEN CAPILLARY FLOW IN PMMA MICROFLUIDIC DEVICES PREPARED BY DIRECT BONDING TECHNIQUE AND PASSIVE SEPARATION OF MICROPARTICLES IN MICROFLUIDIC LABORATORY-ON-A-CHIP SYSTEMS
被引:6
|作者:
Mukhopadhyay, Subhadeep
[1
]
Banerjee, J. P.
[2
]
Mathur, Ashish
[3
]
Tweedie, M.
[4
]
Mclaughlin, J. A.
[4
]
Roy, Susanta Sinha
[5
]
机构:
[1] Inst Engn & Management, Dept Elect & Commun Engn, Kolkata 700091, W Bengal, India
[2] Univ Calcutta, Inst Radio Phys & Elect, Kolkata 700009, W Bengal, India
[3] Amity Univ, Amity Inst Nanotechnol, Noida 201303, Uttar Pradesh, India
[4] Univ Ulster, Nanotechnol & Integrated Bioengn Ctr, Newtownabbey BT37 OQB, North Ireland
[5] Shiv Nadar Univ, Sch Nat Sci, Dept Phys, Gautam Budh Nagar 201314, Uttar Pradesh, India
关键词:
Hot embossing;
direct bonding;
laboratory-on-a-chip;
capillary flow;
DIAMOND-LIKE CARBON;
PLASMA TREATMENT;
MAGNETOPHORESIS;
TECHNOLOGIES;
D O I:
10.1142/S0218625X1550050X
中图分类号:
O64 [物理化学(理论化学)、化学物理学];
学科分类号:
070304 ;
081704 ;
摘要:
Proper bonding technique is investigated to achieve leakage-free surface-driven capillary flow in polymethylmethacrylate (PMMA) microfluidic devices. SU-8-based silicon stamp is fabricated by maskless lithography. This stamp is used to produce PMMA microchannel structure by hot embossing lithography. A direct bonding technique is mainly employed for leakage-free sealing inside PMMA microfluidic devices. The er effect of surface wettability on surface-driven capillary flow is also investigated in PMMA microfluidic devices. The separation of polystyrene microparticles in PMMA laboratory-on-a-chip systems is investigated with the reduction of separation time by air dielectric barrier discharge (DBD) plasma processing of channel surfaces. This study is useful to fabricate the microfluidic laboratory-on-a-chip systems and to understand the surface-driven capillary flow.
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页数:11
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