EXPERIMENTAL STUDIES OF SURFACE-DRIVEN CAPILLARY FLOW IN PMMA MICROFLUIDIC DEVICES PREPARED BY DIRECT BONDING TECHNIQUE AND PASSIVE SEPARATION OF MICROPARTICLES IN MICROFLUIDIC LABORATORY-ON-A-CHIP SYSTEMS

被引:6
|
作者
Mukhopadhyay, Subhadeep [1 ]
Banerjee, J. P. [2 ]
Mathur, Ashish [3 ]
Tweedie, M. [4 ]
Mclaughlin, J. A. [4 ]
Roy, Susanta Sinha [5 ]
机构
[1] Inst Engn & Management, Dept Elect & Commun Engn, Kolkata 700091, W Bengal, India
[2] Univ Calcutta, Inst Radio Phys & Elect, Kolkata 700009, W Bengal, India
[3] Amity Univ, Amity Inst Nanotechnol, Noida 201303, Uttar Pradesh, India
[4] Univ Ulster, Nanotechnol & Integrated Bioengn Ctr, Newtownabbey BT37 OQB, North Ireland
[5] Shiv Nadar Univ, Sch Nat Sci, Dept Phys, Gautam Budh Nagar 201314, Uttar Pradesh, India
关键词
Hot embossing; direct bonding; laboratory-on-a-chip; capillary flow; DIAMOND-LIKE CARBON; PLASMA TREATMENT; MAGNETOPHORESIS; TECHNOLOGIES;
D O I
10.1142/S0218625X1550050X
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
Proper bonding technique is investigated to achieve leakage-free surface-driven capillary flow in polymethylmethacrylate (PMMA) microfluidic devices. SU-8-based silicon stamp is fabricated by maskless lithography. This stamp is used to produce PMMA microchannel structure by hot embossing lithography. A direct bonding technique is mainly employed for leakage-free sealing inside PMMA microfluidic devices. The er effect of surface wettability on surface-driven capillary flow is also investigated in PMMA microfluidic devices. The separation of polystyrene microparticles in PMMA laboratory-on-a-chip systems is investigated with the reduction of separation time by air dielectric barrier discharge (DBD) plasma processing of channel surfaces. This study is useful to fabricate the microfluidic laboratory-on-a-chip systems and to understand the surface-driven capillary flow.
引用
收藏
页数:11
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