Solid pseudopapillary tumor of the pancreas a review of salient clinical and Pathologic features

被引:74
作者
Adams, Amy L. [1 ]
Siegal, Gene P. [1 ]
Jhala, Nirag C. [1 ]
机构
[1] Univ Alabama, Dept Pathol, Birmingham, AL 35249 USA
关键词
SPT; pancreas; solid and papillary epithelial neoplasm; solid cystic pseudopapillary; neoplastic;
D O I
10.1097/PAP.0b013e31815e5237
中图分类号
R36 [病理学];
学科分类号
100104 ;
摘要
Solid pseudopapillary tumor (SPT) of the pancreas is a rare tumor of uncertain histogenesis characterized, as the name suggests, by a cystic and solid pattern of growth with formation of pseudopapillae. Accounting for only a small percentage of pancreatic neoplasms, SPT occurs primarily in young women, although cases in older patients and men have been reported. The tumor is thought to have low-grade malignant potential, as the majority of the cases are cured by simple but complete surgical resection. Knowledge of the unique morphologic and demographic characteristics of this neoplasm is essential for accurate diagnosis. Herein, we review the clinical and pathologic features, which can help separate SPTs from other primary pancreatic tumors.
引用
收藏
页码:39 / 45
页数:7
相关论文
共 56 条
[1]   Solid-pseudopapillary tumors of the pancreas are genetically distinct from pancreatic ductal adenocarcinomas and almost always harbor β-catenin mutations [J].
Abraham, SC ;
Klimstra, DS ;
Wilentz, RE ;
Yeo, CJ ;
Conlon, K ;
Brennan, M ;
Cameron, JL ;
Wu, TT ;
Hruban, RH .
AMERICAN JOURNAL OF PATHOLOGY, 2002, 160 (04) :1361-1369
[2]  
[Anonymous], 1996, WHO I HISTOLOGICAL C
[3]  
[Anonymous], 1959, ATLAS TUMOR PATHOL
[4]  
BALERCIA G, 1995, J SUBMICR CYTOL PATH, V27, P331
[5]   Endoscopic ultrasound-guided fine-needle aspiration cytology diagnosis of solid-pseudopapillary tumor of the pancreas - A rare neoplasm of elusive origin but characteristic cytomorphologic features [J].
Bardales, RH ;
Centeno, B ;
Mallery, JS ;
Lai, R ;
Pochapin, M ;
Guiter, G ;
Stanley, MW .
AMERICAN JOURNAL OF CLINICAL PATHOLOGY, 2004, 121 (05) :654-662
[6]   MR Imaging features of solid pseudopapillary tumor of the pancreas in adult and pediatric patients [J].
Cantisani, V ;
Mortele, KJ ;
Levy, A ;
Glickman, JN ;
Ricci, P ;
Passariello, R ;
Ros, PR ;
Silverman, SG .
AMERICAN JOURNAL OF ROENTGENOLOGY, 2003, 181 (02) :395-401
[7]   Positive immunohistochemical staining of KIT in solid-pseudopapillary neoplasms of the pancreas is not associated with KIT/PDGFRA mutations [J].
Cao, Dengfeng ;
Antonescu, Cristina ;
Wong, Grace ;
Winter, Jordan ;
Maitra, Anirban ;
Adsay, N. Volkan ;
Klimstra, David S. ;
Hruban, Ralph H. .
MODERN PATHOLOGY, 2006, 19 (09) :1157-1163
[8]   NEURON SPECIFIC ENOLASE DEMONSTRATION IN THE DIAGNOSIS OF A SOLID-CYSTIC (PAPILLARY CYSTIC) TUMOR OF THE PANCREAS [J].
CHOTT, A ;
KLOPPEL, G ;
BUXBAUM, P ;
HEITZ, PU .
VIRCHOWS ARCHIV A-PATHOLOGICAL ANATOMY AND HISTOPATHOLOGY, 1987, 410 (05) :397-402
[9]   Solid-pseudopapillary tumor of the pancreas [J].
Coleman, KM ;
Doherty, MC ;
Bigler, SA .
RADIOGRAPHICS, 2003, 23 (06) :1644-1648
[10]   Acinar cell cystadenocarcinoma of the pancreas: Report of rare case and review of the literature [J].
Colombo, P ;
Arizzi, C ;
Roncalli, M .
HUMAN PATHOLOGY, 2004, 35 (12) :1568-1571