Antioxidant and prooxidant properties of flavonoids

被引：1082
作者：
Prochazkova, D. [1 ]
Bousova, I. [2 ]
Wilhelmova, N. [1 ]
机构：
[1] Acad Sci Czech Republ, Inst Expt Bot, Prague, Czech Republic
[2] Charles Univ Prague, Dept Biochem Sci, Fac Pharm Hradec Kralove, CR-11636 Prague 1, Czech Republic
来源：
FITOTERAPIA | 2011年 / 82卷 / 04期
关键词：
Phenoxyl radical; Antioxidants; Prooxidants; LOW-DENSITY-LIPOPROTEIN; NITRIC-OXIDE PRODUCTION; CORONARY-HEART-DISEASE; GREEN TEA POLYPHENOLS; ACID SODIUM-SALT; ALPHA-TOCOPHEROL; RED WINE; LIPID-PEROXIDATION; HYDROGEN-PEROXIDE; BETA-CAROTENE;
D O I：
10.1016/j.fitote.2011.01.018
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
The interest in possible health benefits of flavonoids has increased owing to their potent antioxidant and free radical scavenging activities observed in vitro. Nevertheless, the antioxidant efficacy of flavonoids in vivo is less documented and their prooxidant properties have been actually described in vivo. Due to their prooxidant properties, they are able to cause oxidative damage by reacting with various biomolecules, such as lipids, proteins and DNA. Hence, the aim of this review is to discuss both the antioxidant and prooxidant effects of flavonoids. (C) 2011 Elsevier B.V. All rights reserved.
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页码：513 / 523
页数：11
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