Necrotic enteritis in chickens: a review of pathogenesis, immune responses and prevention, focusing on probiotics and vaccination

被引：47
作者：
Alizadeh, Mohammadali [1 ]
Shojadoost, Bahram [1 ]
Boodhoo, Nitish [1 ]
Astill, Jake [2 ]
Taha-Abdelaziz, Khaled [3 ]
Hodgins, Douglas C. [1 ]
Kulkarni, Raveendra R. [4 ]
Sharif, Shayan [1 ]
机构：
[1] Univ Guelph, Ontario Vet Coll, Dept Pathobiol, Guelph, ON N1G 2W1, Canada
[2] Artemis Technol Inc, Guelph, ON, Canada
[3] Clemson Univ, Dept Anim & Vet Sci, Clemson, SC 29634 USA
[4] North Carolina State Univ, Coll Vet Med, Dept Populat Hlth & Pathobiol, Raleigh, NC 27607 USA
来源：
ANIMAL HEALTH RESEARCH REVIEWS | 2021年 / 22卷 / 02期
关键词：
Chickens; Clostridium perfringens; immune response; necrotic enteritis; pathogenesis; probiotics; vaccination; CLOSTRIDIUM-PERFRINGENS STRAINS; LACTIC-ACID BACTERIA; T-CELL SUBSETS; BROILER-CHICKENS; GROWTH-PERFORMANCE; ALPHA-TOXIN; SALMONELLA-ENTERICA; GENE-EXPRESSION; ANTIMICROBIAL PEPTIDES; CYTOKINE RESPONSES;
D O I：
10.1017/S146625232100013X
中图分类号：
S85 [动物医学（兽医学）];
学科分类号：
0906 ;
摘要：
Necrotic enteritis (NE), caused by Clostridium perfringens (CP), is one of the most common of poultry diseases, causing huge economic losses to the poultry industry. This review provides an overview of the pathogenesis of NE in chickens and of the interaction of CP with the host immune system. The roles of management, nutrition, probiotics, and vaccination in reducing the incidence and severity of NE in poultry flocks are also discussed.
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收藏
页码：147 / 162
页数：16
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