Bioinformatics Tools for Small Genomes, Such as Hepatitis B Virus

被引：22
作者：
Bell, Trevor G. [1 ]
Kramvis, Anna [1 ]
机构：
[1] Univ Witwatersrand, Dept Internal Med, Fac Hlth Sci, HVDRP,Sch Clin Med, ZA-2050 Johannesburg, South Africa
来源：
VIRUSES-BASEL | 2015年 / 7卷 / 02期
基金：
新加坡国家研究基金会; 英国医学研究理事会;
关键词：
AMINO-ACID-SEQUENCE; MONOCLONAL-ANTIBODIES; SUBTYPES; GENOTYPES;
D O I：
10.3390/v7020781
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
DNA sequence analysis is undertaken in many biological research laboratories. The workflow consists of several steps involving the bioinformatic processing of biological data. We have developed a suite of web-based online bioinformatic tools to assist with processing, analysis and curation of DNA sequence data. Most of these tools are genome-agnostic, with two tools specifically designed for hepatitis B virus sequence data. Tools in the suite are able to process sequence data from Sanger sequencing, ultra-deep amplicon resequencing (pyrosequencing) and chromatograph (trace files), as appropriate. The tools are available online at no cost and are aimed at researchers without specialist technical computer knowledge. The tools can be accessed at http://hvdr.bioinf.wits.ac.za/SmallGenomeTools, and the source code is available online at https://github.com/DrTrevorBell/SmallGenomeTools.
引用
收藏
页码：781 / 797
页数：17
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