Diagnostic thresholds for free light chains in multiple myeloma depend on the assay used

被引：20

作者：

Bossuyt, Xavier ^{[1
,2
]}

Delforge, Michel ^{[3
]}

Reynders, Martin ^{[1
]}

Dillaerts, Doreen ^{[2
]}

Sprangers, Ben ^{[4
]}

Fostier, Karel ^{[5
]}

Poesen, Koen ^{[1
,6
]}

Vercammen, Martine ^{[7
,8
]}

机构：

[1] Univ Hosp Leuven, Lab Med, Immunol, Leuven, Belgium

[2] Katholieke Univ Leuven, Dept Microbiol & Immunol, Expt Immunol Lab, Leuven, Belgium

[3] Univ Hosp Leuven, Dept Hematol, Leuven, Belgium

[4] Univ Hosp Leuven, Dept Nephrol, Leuven, Belgium

[5] Univ Hosp VUB, Dept Hematol, Brussels, Belgium

[6] Katholieke Univ Leuven, Lab Mol Neurobiomarker Res, Dept Neurosci, Leuven, Belgium

[7] Univ Ziekenhuis Brussel VUB, Hematol Lab, Brussels, Belgium

[8] Acad Hosp St Jan, Dept Lab Med, Brugge, Belgium

来源：

LEUKEMIA | 2018年 / 32卷 / 08期

关键词：

N LATEX FLC; SERUM; CRITERIA; PERFORMANCE; URINE;

D O I：

10.1038/s41375-018-0041-0

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

[No abstract available]

引用

页码：1815 / 1818

页数：4

共 11 条

[1]

Bradwell AR, 2001, CLIN CHEM, V47, P673

[2] Analytical issues of serum free light chain assays and the relative performance of polyclonal and monoclonal based reagents [J].

Carr-Smith, Hugh D. ;

Jenner, Ellen L. ;

Evans, Josie A. R. ;

Harding, Stephen J. .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2016, 54 (06) :997-1003

[3] Criteria for diagnosis, staging, risk stratification and response assessment of multiple myeloma [J].

Kyle, R. A. ;

Rajkumar, S. V. .

LEUKEMIA, 2009, 23 (01) :3-9

[4] Serum free light chain ratio as a biomarker for high-risk smoldering multiple myeloma [J].

Larsen, J. T. ;

Kumar, S. K. ;

Dispenzieri, A. ;

Kyle, R. A. ;

Katzmann, J. A. ;

Rajkumar, S. V. .

LEUKEMIA, 2013, 27 (04) :941-946

[5] Circulating free light chain measurement in the diagnosis, prognostic assessment and evaluation of response of AL amyloidosis: comparison of Freelite and N latex FLC assays [J].

Palladini, Giovanni ;

Jaccard, Arnaud ;

Milani, Paolo ;

Lavergne, David ;

Foli, Andrea ;

Bender, Sebastien ;

Lavatelli, Francesca ;

Bosoni, Tiziana ;

Valentini, Veronica ;

Pirolini, Laura ;

Ferraro, Giovanni ;

Basset, Marco ;

Russo, Francesca ;

Nuvolone, Mario ;

Albertini, Riccardo ;

Cogne, Michel ;

Merlini, Giampaolo .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2017, 55 (11) :1734-1743

[6] New Criteria for Response to Treatment in Immunoglobulin Light Chain Amyloidosis Based on Free Light Chain Measurement and Cardiac Biomarkers: Impact on Survival Outcomes [J].

Palladini, Giovanni ;

Dispenzieri, Angela ;

Gertz, Morie A. ;

Kumar, Shaji ;

Wechalekar, Ashutosh ;

Hawkins, Philip N. ;

Schoenland, Stefan ;

Hegenbart, Ute ;

Comenzo, Raymond ;

Kastritis, Efstathios ;

Dimopoulos, Meletios A. ;

Jaccard, Arnaud ;

Klersy, Catherine ;

Merlini, Giampaolo .

JOURNAL OF CLINICAL ONCOLOGY, 2012, 30 (36) :4541-4549

[7] Identification of Amyloidogenic Light Chains Requires the Combination of Serum-Free Light Chain Assay with Immunofixation of Serum and Urine [J].

Palladini, Giovanni ;

Russo, Paola ;

Bosoni, Tiziana ;

Verga, Laura ;

Sarais, Gabriele ;

Lavatelli, Francesca ;

Nuvolone, Mario ;

Obici, Laura ;

Casarini, Simona ;

Donadei, Simona ;

Albertini, Riccardo ;

Righetti, Gabriella ;

Marini, Maddalena ;

Graziani, Maria Stella ;

D'Eril, Gian Vico Melzi ;

Moratti, Remigio ;

Merlini, Giampaolo .

CLINICAL CHEMISTRY, 2009, 55 (03) :499-504

[8] International Myeloma Working Group updated criteria for the diagnosis of multiple myeloma [J].

Rajkumar, S. Vincent ;

Dimopoulos, Meletios A. ;

Palumbo, Antonio ;

Blade, Joan ;

Merlini, Giampaolo ;

Mateos, Maria-Victoria ;

Kumar, Shaji ;

Hillengass, Jens ;

Kastritis, Efstathios ;

Richardson, Paul ;

Landgren, Ola ;

Paiva, Bruno ;

Dispenzieri, Angela ;

Weiss, Brendan ;

Leleu, Xavier ;

Zweegman, Sonja ;

Lonial, Sagar ;

Rosinol, Laura ;

Zamagni, Elena ;

Jagannath, Sundar ;

Sezer, Orhan ;

Kristinsson, Sigurdur Y. ;

Caers, Jo ;

Usmani, Saad Z. ;

Lahuerta, Juan Jose ;

Johnsen, Hans Erik ;

Beksac, Meral ;

Cavo, Michele ;

Goldschmidt, Hartmut ;

Terpos, Evangelos ;

Kyle, Robert A. ;

Anderson, Kenneth C. ;

Durie, Brian G. M. ;

San Miguel, Jesus F. .

LANCET ONCOLOGY, 2014, 15 (12) :E538-E548

[9] Serum free light chain ratio is an independent risk factor for progression in monoclonal gammopathy of undetermined significance [J].

Rajkumar, SV ;

Kyle, RA ;

Therneau, TM ;

Melton, LJ ;

Bradwell, AR ;

Clark, RJ ;

Larson, DR ;

Plevak, MF ;

Dispenzieri, A ;

Katzmann, JA .

BLOOD, 2005, 106 (03) :812-817

[10] N Latex FLC - new monoclonal high-performance assays for the determination of free light chain kappa and lambda [J].

Velthuis, Henk Te ;

Knop, Ingrid ;

Stam, Peter ;

van den Broek, Monic ;

Bos, Hannie Klaasse ;

Hol, Suzanne ;

Teunissen, Elisa ;

Fischedick, Karin Schulte ;

Althaus, Harald ;

Schmidt, Brigitta ;

Wagner, Carola ;

Melsert, Roel .

CLINICAL CHEMISTRY AND LABORATORY MEDICINE, 2011, 49 (08) :1323-1332

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