Induced circularly polarized luminescence arising from anion or protein binding to racemic emissive lanthanide complexes

被引：36

作者：

Carr, Rachel ^{[1
]}

Puckrin, Robert ^{[1
]}

McMahon, Brian K. ^{[1
]}

Pal, Robert ^{[1
]}

Parker, David ^{[1
]}

Palsson, Lars-Olof ^{[1
]}

机构：

[1] Univ Durham, Dept Chem, Durham DH1 3LE, England

来源：

METHODS AND APPLICATIONS IN FLUORESCENCE | 2014年 / 2卷 / 02期

基金：

英国工程与自然科学研究理事会;

关键词：

circular polarisation; lanthanide complexes; chiral interactions; optical spectroscopy; biological systems; DIAQUA-YTTERBIUM; EXCITED-STATES; AMINO-ACIDS; EUROPIUM; TRIAZACYCLONONANE; SELECTIVITY; TERBIUM; PROBE; FIELD; ASSAY;

D O I：

10.1088/2050-6120/2/2/024007

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

A circularly polarized luminescence (CPL) spectrometer has been built and used to study the binding interaction of lactate and four different proteins with racemic Eu-III and Tb-III complexes in aqueous solution. Lactate binding gives rise to strong induced CPL spectra, and the observed emission dissymmetry factors vary linearly with enantiomeric composition. Particularly strong induced Tb-III CPL also characterizes the binding interaction of alpha-1-acid glycoprotein with a dissociation constant, K-d, of 2.5 mu M.

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页数：7

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