Evolutionary Physiology of Bone: Bone Metabolism in Changing Environments

被引:71
作者
Doherty, Alison H. [1 ]
Ghalambor, Cameron K. [2 ,3 ]
Donahue, Seth W. [1 ]
机构
[1] Colorado State Univ, Dept Mech Engn, Flint Anim Canc Ctr, Ft Collins, CO 80523 USA
[2] Colorado State Univ, Dept Biol, Ft Collins, CO 80523 USA
[3] Colorado State Univ, Grad Degree Program Ecol, Ft Collins, CO 80523 USA
关键词
CORTICAL BONE; MAMMALIAN HIBERNATION; MECHANICAL-PROPERTIES; CALCIUM HOMEOSTASIS; SIGNAL-TRANSDUCTION; PARATHYROID-HORMONE; COSTAL COMPACTA; ACELLULAR BONE; FATIGUE DAMAGE; MEDULLARY BONE;
D O I
10.1152/physiol.00022.2014
中图分类号
Q4 [生理学];
学科分类号
071003 ;
摘要
Bone evolved to serve many mechanical and physiological functions. Osteocytes and bone remodeling first appeared in the dermal skeleton of fish, and subsequently adapted to various challenges in terrestrial animals occupying diverse environments. This review discusses the physiology of bone and its role in mechanical and calcium homeostases from an evolutionary perspective. We review how bone physiology responds to changing environments and the adaptations to unique and extreme physiological conditions.
引用
收藏
页码:17 / 29
页数:13
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