Bacteria from Animals as a Pool of Antimicrobial Resistance Genes

被引:194
作者
Argudin, Maria Angeles [1 ]
Deplano, Ariane [1 ]
Meghraoui, Alaeddine [1 ]
Dodemont, Magali [1 ]
Heinrichs, Amelie [1 ]
Denis, Olivier [1 ,2 ]
Nonhoff, Claire [1 ]
Roisin, Sandrine [1 ]
机构
[1] Univ Libre Bruxelles, Dept Microbiol, Natl Reference Ctr Staphylococcus Aureus, Hop Erasme, Route Lennik 808, B-1070 Brussels, Belgium
[2] Univ Libre Bruxelles, Ecole Sante Publ, Ave Franklin Roosevelt 50, B-1050 Brussels, Belgium
来源
ANTIBIOTICS-BASEL | 2017年 / 6卷 / 02期
关键词
mec; cfr; mcr; CASSETTE CHROMOSOME MEC; STAPHYLOCOCCUS-AUREUS ST398; MACROLIDE-LINCOSAMIDE-STREPTOGRAMIN; CARRYING TRANSPOSON TN559; CFR-LIKE GENE; ESCHERICHIA-COLI; ANTIBIOTIC-RESISTANCE; ACINETOBACTER-BAUMANNII; PSEUDOMONAS-AERUGINOSA; CLOSTRIDIUM-DIFFICILE;
D O I
10.3390/antibiotics6020012
中图分类号
R51 [传染病];
学科分类号
100401 ;
摘要
Antimicrobial agents are used in both veterinary and human medicine. The intensive use of antimicrobials in animals may promote the fixation of antimicrobial resistance genes in bacteria, which may be zoonotic or capable to transfer these genes to human-adapted pathogens or to human gut microbiota via direct contact, food or the environment. This review summarizes the current knowledge of the use of antimicrobial agents in animal health and explores the role of bacteria from animals as a pool of antimicrobial resistance genes for human bacteria. This review focused in relevant examples within the ESC(K)APE (Enterococcus faecium, Staphylococcus aureus, Clostridium difficile (Klebsiella pneumoniae), Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae) group of bacterial pathogens that are the leading cause of nosocomial infections throughout the world.
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页数:38
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