Absence of the NLRP-3 inflammasome protects against the development of obesity and insulin resistance

被引:0
|
作者
Stienstra, R. [1 ,3 ]
van Diepen, J. A. [2 ]
Tack, C. J. [3 ]
Rensen, P. C. N. [2 ]
Joosten, L. A. B. [3 ]
Netea, M. G. [3 ]
Kanneganti, T. Devi [1 ]
机构
[1] St Jude Childrens Hosp, Dept Immunol, Memphis, TN 38105 USA
[2] Leiden Univ, Med Ctr, Dept Internal Med Endocrinol & Metab Dis, NL-2300 RA Leiden, Netherlands
[3] Gen Internal Med, Nijmegen, Netherlands
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
810
引用
收藏
页数:1
相关论文
共 50 条
  • [41] Hydrogen sulfide protects against DSS-induced colitis by inhibiting NLRP3 inflammasome
    Qin, Ming
    Long, Fen
    Wu, Weijun
    Yang, Di
    Huang, Mengwei
    Xiao, Chenxi
    Chen, Xu
    Liu, Xinhua
    Zhu, Yi Zhun
    FREE RADICAL BIOLOGY AND MEDICINE, 2019, 137 : 99 - 109
  • [42] Scutellarin Suppresses NLRP3 Inflammasome Activation in Macrophages and Protects Mice against Bacterial Sepsis
    Liu, Yi
    Jing, Yan-Yun
    Zeng, Chen-Ying
    Li, Chen-Guang
    Xu, Li-Hui
    Yan, Liang
    Bai, Wen-Jing
    Zha, Qing-Bing
    Ouyang, Dong-Yun
    He, Xian-Hui
    FRONTIERS IN PHARMACOLOGY, 2018, 8
  • [43] Polydatin protects against atherosclerosis by activating autophagy and inhibiting pyroptosis mediated by the NLRP3 inflammasome
    Zhang, Xiaonan
    Wang, Zeping
    Li, Xiaoya
    Chen, Jiye
    Yu, Zongliang
    Li, Xin
    Sun, Changxin
    Hu, Lanqing
    Wu, Min
    Liu, Longtao
    JOURNAL OF ETHNOPHARMACOLOGY, 2023, 309
  • [44] Artemisinin protects mice against burn sepsis through inhibiting NLRP3 inflammasome activation
    Long, Huibao
    Xu, Bincan
    Luo, Yanling
    Luo, Keqin
    AMERICAN JOURNAL OF EMERGENCY MEDICINE, 2016, 34 (05): : 772 - 777
  • [45] Inflammasome is a central player in the induction of obesity and insulin resistance
    Stienstra, Rinke
    van Diepen, Janna A.
    Tack, Cees J.
    Zaki, Md. Hasan
    van de Veerdonk, Frank L.
    Perera, Deshani
    Neale, Geoffrey A.
    Hooiveld, Guido J.
    Hijmans, Anneke
    Vroegrijk, Irene
    van den Berg, Sjoerd
    Romijn, Johannes
    Rensen, Patrick C. N.
    Joosten, Leo A. B.
    Netea, Mihai G.
    Kanneganti, Thirumala-Devi
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2011, 108 (37) : 15324 - 15329
  • [46] The NLRP3 Inflammasome Protects against Loss of Epithelial Integrity and Mortality during Experimental Colitis
    Zaki, Md. Hasan
    Boyd, Kelli L.
    Vogel, Peter
    Kastan, Michael B.
    Lamkanfi, Mohamed
    Kanneganti, Thirumala-Devi
    IMMUNITY, 2010, 32 (03) : 379 - 391
  • [47] Involvement of NLRP3 inflammasome in the impacts of sodium and potassium on insulin resistance in normotensive Asians
    Wan, Zhaofei
    Wen, Wen
    Ren, Keyu
    Zhou, Dong
    Liu, Junhui
    Wu, Yue
    Zhou, Juan
    Mu, Jianjun
    Yuan, Zuyi
    BRITISH JOURNAL OF NUTRITION, 2018, 119 (02) : 228 - 237
  • [48] Arsenic induces hepatic insulin resistance via mtROS-NLRP3 inflammasome pathway
    Jia, Xue
    Qiu, Tianming
    Yao, Xiaofeng
    Jiang, Liping
    Wang, Ningning
    Wei, Sen
    Tao, Ye
    Pei, Pei
    Wang, Zhidong
    Zhang, Jingyuan
    Zhu, Yuhan
    Yang, Guang
    Liu, Xiaofang
    Liu, Shuang
    Sun, Xiance
    JOURNAL OF HAZARDOUS MATERIALS, 2020, 399
  • [49] Overexpression of insulin-like growth factor binding protein-2 in mice protects against the development of insulin resistance and obesity
    Wheatcroft, S
    Crossey, P
    Ezzat, V
    Modo, M
    Williams, S
    Miell, J
    Shah, A
    Kearney, M
    CIRCULATION, 2004, 110 (17) : 88 - 89
  • [50] NLRP-3 Inflammasome: A Key Target, but Mostly Overlooked following SARS-CoV-2 Infection
    Sergi, Consolato M.
    VACCINES, 2022, 10 (08)