Genetic diversity and effect of inbreeding on litter size of the Romanov sheep

被引：20
作者：
Vostry, L. [1 ]
Milerski, M. [2 ]
Schmidova, J. [2 ]
Vostra-Vydrova, H. [2 ]
机构：
[1] Czech Univ Life Sci Prague, Fac Agrobiol Food & Nat Resources, Prague, Czech Republic
[2] Inst Anim Sci, Prague, Czech Republic
来源：
SMALL RUMINANT RESEARCH | 2018年 / 168卷
关键词：
Inbreeding; Inbreeding depression; Litter size; EFFECTIVE POPULATION-SIZE; PEDIGREE ANALYSIS; DEPRESSION; VARIABILITY; MANAGEMENT; COEFFICIENTS; TRAITS; GROWTH;
D O I：
10.1016/j.smallrumres.2018.09.004
中图分类号：
S8 [畜牧、 动物医学、狩猎、蚕、蜂];
学科分类号：
0905 ;
摘要：
The objective of the present study was to describe the population structure and quantify the effect of inbreeding on litter size in Romanov sheep in the Czech Republic. The analysis was based on the pedigree information of 26,447 animals. The numbers of generations were 19, with average equivalent known generations of 6.41. The effective numbers of founders and ancestors contributing to the current genetic pool were, respectively, 92.96 and 47.41 respectively. The average inbreeding coefficients were 5.5% and the average inbreeding rate was 1%. The corresponding estimates of effective population size were 48.28 and 45.64, based on an individual increase in inbreeding or coancestry, respectively. Classical inbreeding coefficient and two kinds of new inbreeding coefficient were used to quantify the effect of inbreeding. The effect of all tested kind of inbreeding on litter size was statistically significant, but very small (around -0.05 lambs per change of 1% in inbreeding). Statistical difference measured by Delta AICc was not-significant. These statistics suggest that the genetic variability has decreased and inbreeding depression is occurred, and without changes in breeding strategy the genetic variability might continue to decline.
引用
收藏
页码：25 / 31
页数：7
相关论文
共 40 条
  • [1] [Anonymous], 2002, Model selection and multimodel inference: a practical informationtheoretic approach
  • [2] Banos E. A., 2017, SMALL RUMINANT RES, V149, P128, DOI [10.1016/j.smallrumres.2017.02.009, DOI 10.1016/J.SMALLRUMRES.2017.02.009]
  • [3] GRAIN: a computer program to calculate ancestral and partial inbreeding coefficients using a gene dropping approach
    Baumung, R.
    Farkas, J.
    Boichard, D.
    Meszaros, G.
    Soelkner, J.
    Curik, I.
    [J]. JOURNAL OF ANIMAL BREEDING AND GENETICS, 2015, 132 (02) : 100 - 108
  • [4] The value of using probabilities of gene origin to measure genetic variability in a population
    Boichard, D
    Maignel, L
    Verrier, E
    [J]. GENETICS SELECTION EVOLUTION, 1997, 29 (01) : 5 - 23
  • [5] Interrelations between effective population size and other pedigree tools for the management of conserved populations
    Caballero, A
    Toro, MA
    [J]. GENETICS RESEARCH, 2000, 75 (03) : 331 - 343
  • [6] DEVELOPMENTS IN THE PREDICTION OF EFFECTIVE POPULATION-SIZE
    CABALLERO, A
    [J]. HEREDITY, 1994, 73 : 657 - 679
  • [7] Estimation of effective population size from the rate of coancestry in pedigreed populations
    Cervantes, I.
    Goyache, F.
    Molina, A.
    Valera, M.
    Gutierrez, J. P.
    [J]. JOURNAL OF ANIMAL BREEDING AND GENETICS, 2011, 128 (01) : 56 - 63
  • [8] The variant call format and VCFtools
    Danecek, Petr
    Auton, Adam
    Abecasis, Goncalo
    Albers, Cornelis A.
    Banks, Eric
    DePristo, Mark A.
    Handsaker, Robert E.
    Lunter, Gerton
    Marth, Gabor T.
    Sherry, Stephen T.
    McVean, Gilean
    Durbin, Richard
    [J]. BIOINFORMATICS, 2011, 27 (15) : 2156 - 2158
  • [9] Pedigree analysis of seven small French sheep populations and implications for the management of rare breeds
    Danchin-Burge, C.
    Palhiere, I.
    Francois, D.
    Bibe, B.
    Leroy, G.
    Verrier, E.
    [J]. JOURNAL OF ANIMAL SCIENCE, 2010, 88 (02) : 505 - 516
  • [10] Inbreeding and its impact on the prolific Polish Olkuska sheep population
    Drobik, W.
    Martyniuk, E.
    [J]. SMALL RUMINANT RESEARCH, 2016, 137 : 28 - 33
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