Diversity-oriented approach to 1,2-dihydroisoquinolin-3(4H)-imines via copper(I)-catalyzed reaction of (E)-2-ethynylphenylchalcone, sulfonyl azide and amine

被引：52

作者：

Chen, Zhiyuan ^{[2
,3
]}

Ye, Chao ^{[2
,3
]}

Gao, Liang ^{[2
,3
]}

Wu, Jie ^{[1
]}

机构：

[1] Fudan Univ, Dept Chem, Shanghai 200433, Peoples R China

[2] Jiangxi Normal Univ, Key Lab Funct Small Organ Mol, Minist Educ, Nanchang 330022, Jiangxi, Peoples R China

[3] Jiangxi Normal Univ, Coll Chem & Chem Engn, Nanchang 330022, Jiangxi, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2011年 / 47卷 / 19期

基金：

中国国家自然科学基金;

关键词：

ONE-POT SYNTHESIS; CATALYZED MULTICOMPONENT REACTION; FRITSCH-BOBBITT SYNTHESIS; FACILE ACCESS; ASYMMETRIC-SYNTHESIS; EFFICIENT SYNTHESIS; TETRAHYDROISOQUINOLINE DERIVATIVES; SYNTHETIC UTILITY; RECENT PROGRESS; AMIDE SYNTHESIS;

D O I：

10.1039/c1cc11176k

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A three-component reaction of (E)-2-ethynylphenylchalcone, sulfonyl azide, and amine catalyzed by copper(I) chloride (5 mol%), in the presence of triethylamine, under mild conditions is described. This transformation proceeds efficiently to generate 1,2-dihydroisoquinolin-3(4H)-imines in good to excellent yields.

引用

页码：5623 / 5625

页数：3

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