Potential sonodynamic anticancer activities of artemether and liposome-encapsulated artemether

被引：44
作者：
Chen, Hai-Jun [1 ]
Huang, Xiu-Rong [1 ]
Zhou, Xiao-Bin [1 ]
Zheng, Bi-Yuan [1 ]
Huang, Jian-Dong [1 ]
机构：
[1] Fuzhou Univ, State Key Lab Photocatalysis Energy & Environm, Coll Chem, Fuzhou 350116, Peoples R China
来源：
CHEMICAL COMMUNICATIONS | 2015年 / 51卷 / 22期
基金：
中国国家自然科学基金;
关键词：
TRIOXANE DIMERS; DRUG DISCOVERY; CANCER-THERAPY; HIGH-STABILITY; ANTIMALARIAL; ULTRASOUND; PACLITAXEL; MECHANISM; EFFICACY; TRICKS;
D O I：
10.1039/c5cc00927h
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
The potential application of artemether as a novel sonosensitizer for sonodynamic therapy (SDT) was explored and illustrated for the first time. In addition, liposome-encapsulated artemether exhibited significantly enhanced sonodynamic anticancer activity. Our findings indicated that artemisinin derivatives may serve as a new kind of sonosensitizer for SDT.
引用
收藏
页码：4681 / 4684
页数：4
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