Single-molecule fluorescence spectroscopy of protein folding

被引：124

作者：

Schuler, B ^{[1
]}

机构：

[1] Univ Zurich, Dept Biochem, CH-8057 Zurich, Switzerland

来源：

CHEMPHYSCHEM | 2005年 / 6卷 / 07期

关键词：

emission spectroscopy; FRET (fluorescence resonance energy transfer); protein folding; proteins; single-molecule studies;

D O I：

10.1002/cphc.200400609

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

Single-molecule spectroscopy is an important new approach for studying the intrinsically heterogeneous process of protein folding. This Review illustrates how different single-molecule fluorescence techniques have improved our understanding of mechanistic aspects in protein folding, exemplified by a series of recent experiments on a small protein.

引用

页码：1206 / 1220

页数：15

共 50 条

[21] Structure and Dynamics in Protein Folding from Single Molecule Fluorescence Spectroscopy
Schuler, Benjamin
BIOPHYSICAL JOURNAL, 2011, 100 (03) : 373 - 373
[22] Studies of protein folding and dynamics using single molecule fluorescence spectroscopy
Basak, Sujit
Chattopadhyay, Krishnananda
PHYSICAL CHEMISTRY CHEMICAL PHYSICS, 2014, 16 (23) : 11139 - 11149
[23] Single-Molecule Fluorescence Experiments Determine Protein Folding Transition Path Times
Chung, Hoi Sung
McHale, Kevin
Louis, John M.
Eaton, William A.
SCIENCE, 2012, 335 (6071) : 981 - 984
[24] Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
Alessandro Borgia
Beth G. Wensley
Andrea Soranno
Daniel Nettels
Madeleine B. Borgia
Armin Hoffmann
Shawn H. Pfeil
Everett A. Lipman
Jane Clarke
Benjamin Schuler
Nature Communications, 3
[25] Localizing internal friction along the reaction coordinate of protein folding by combining ensemble and single-molecule fluorescence spectroscopy
Borgia, Alessandro
Wensley, Beth G.
Soranno, Andrea
Nettels, Daniel
Borgia, Madeleine B.
Hoffmann, Armin
Pfeil, Shawn H.
Lipman, Everett A.
Clarke, Jane
Schuler, Benjamin
NATURE COMMUNICATIONS, 2012, 3
[26] Protein folding studied by single-molecule FRET
Schuler, Benjamin
Eaton, William A.
CURRENT OPINION IN STRUCTURAL BIOLOGY, 2008, 18 (01) : 16 - 26
[27] Single-molecule measurement of protein folding kinetics
Lipman, EA
Schuler, B
Bakajin, O
Eaton, WA
SCIENCE, 2003, 301 (5637) : 1233 - 1235
[28] Single-molecule protein-folding kinetics
不详
CHEMICAL & ENGINEERING NEWS, 2003, 81 (35) : 28 - 28
[29] Dynamics of Protein Folding and Cofactor Binding Monitored by Single-Molecule Force Spectroscopy
Cao, Yi
Li, Hongbin
BIOPHYSICAL JOURNAL, 2011, 101 (08) : 2009 - 2017
[30] Single-Molecule Studies of Multidomain Protein Folding
Liu, Kaixian
Kaiser, Christian
BIOPHYSICAL JOURNAL, 2015, 108 (02) : 521A - 521A

← 1 2 3 4 5 →