Asymmetric azidoselenenylation of alkenes: A key step for the synthesis of enantiomerically enriched nitrogen-containing compounds

被引：118

作者：

Tiecco, M ^{[1
]}

Testaferri, L ^{[1
]}

Santi, C ^{[1
]}

Tomassini, C ^{[1
]}

Marini, F ^{[1
]}

Bagnoli, L ^{[1
]}

Temperini, A ^{[1
]}

机构：

[1] Univ Perugia, Dipartimento Chim & Tecnol Farmaco, Sez Chim Organ, I-06123 Perugia, Italy

来源：

ANGEWANDTE CHEMIE-INTERNATIONAL EDITION | 2003年 / 42卷 / 27期

关键词：

alkenes; asymmetric synthesis; azides; heterocycles; selenium;

D O I：

10.1002/anie.200351229

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Chiral, nonracemic azidoselenides such as 2 are useful intermediates for the synthesis of enantiomerically enriched nitrogen-containing compounds (e.g. 3). The asymmetric electrophilic azidoselenenylation of a variety of alkenes with the sulfur-containing chiral selenenyl triflate 1 and sodium azide occurred with high facial selectivity to provide an array of azidoselenides, which were further elaborated.

引用

页码：3131 / 3133

页数：3

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