A transparent model of the human scala tympani cavity

被引:23
作者
Rebscher, SJ
Talbot, N
Bruszewski, W
Heilmann, M
Brasell, J
Merzenich, MM
机构
[1] Coleman and Epstein Mem. Labs., Department of Otolaryngology, University of California, San Francisco
关键词
cochlear implant; cochlea; scala tympani; electrical stimulation; biomedical modelling;
D O I
10.1016/0165-0270(95)00116-6
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
A dimensionally accurate clear model of the human scala tympani has been produced to evaluate the insertion and position of clinically applied intracochlear electrodes for electrical stimulation. Replicates of the human scala tympani were made from low melting point metal alloy (LMA) and from polymethylmeth-acrylate (PMMA) resin. The LMA metal casts were embedded in blocks of epoxy and in clear silicone rubber. After removal of the metal alloy, a cavity was produced that accurately models the human scala tympani. Investment casting molds were made from the PMMA scala tympani casts to enable production of multiple LMA casts from which identical models were fabricated. Total dimensional distortion of the LMA casting process was less than 1% in length and 2% in diameter. The models have been successfully integrated into the design process for the iterative development of advanced intracochlear electrode arrays at UCSF. These fabrication techniques are applicable to a wide range of biomedical design problems that require modelling of visually obscured cavities.
引用
收藏
页码:105 / 114
页数:10
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