Surgical management of extra-regional lymph node metastasis in colorectal cancer

被引：16

作者：

Albandar, Mahdi H. ^{[1
]}

Cho, Min Soo ^{[1
]}

Bae, Sung Uk ^{[1
]}

Kim, Nam Kyu ^{[1
]}

机构：

[1] Yonsei Univ, Dept Surg, Coll Med, Seoul 120749, South Korea

来源：

EXPERT REVIEW OF ANTICANCER THERAPY | 2016年 / 16卷 / 05期

关键词：

Extra-regional; lymph node; colorectal cancer; surgical management and metastasis; LOW-RECTAL-CANCER; TOTAL MESORECTAL EXCISION; RESECTABLE LIVER METASTASES; PELVIC SIDEWALL DISSECTION; PREOPERATIVE RADIOTHERAPY; EXTENDED LYMPHADENECTOMY; CURATIVE RESECTION; CONTROLLED-TRIAL; PLUS IRINOTECAN; SURGERY;

D O I：

10.1586/14737140.2016.1162718

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

One of the major problems in rectal cancer surgery is local recurrence, found in an average of 21% to 46% cases in 1990. However, the advent of chemo-radiotherapy (CRT) and total mesorectal excision (TME) improve local control and enhances survival rates in colorectal cancer (CRC). Regional lymph node involvement is determined to be an independent prognostic factor in local recurrence; however, extra-regional lymph node (ERLN) metastasis has a higher recurrence rate (up to 58.1%). Lack of supportive data in management of ERLN metastasis in CRC has added further strain and challenges to structure a unique treatment strategy. ERLN refers to extra-mesenteric involvement either in the para-aortic lymph node (PALN) or the lateral pelvic lymph node (LPLN). Treatment of ERLN metastasis is challenging because of the shortage of the resources. Here, we will outline and summarize approaches and management of ERLN metastasis. We also aim to clarify the role of surgical intervention in CRC

引用

页码：503 / 513

页数：11

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