Effect of cavity margin shavings to completeness of excision on local ensure recurrence rates following breast conserving surgery

被引:27
作者
Barthelmes, L [1 ]
Al Awa, A [1 ]
Crawford, DJ [1 ]
机构
[1] Llandudno Gen Hosp, Dept Surg, Brest Unit, Llandudno LL30 1LB, Wales
来源
EUROPEAN JOURNAL OF SURGICAL ONCOLOGY | 2003年 / 29卷 / 08期
关键词
cavity margin shavings; local recurrence rate; excision;
D O I
10.1016/S0748-7983(03)00122-7
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Aims: The presence of residual disease at the excision margin after breast conserving surgery is the most important risk factor for local recurrence. One method for assessing tumour margin involvement is to take shavings from the wall of the resulting cavity following wide excision of the lesion. Methods: We have reviewed our experience of shaving the margin of the cavity as our method to ensure completeness of excision. Results: Of 351 patients treated with breast conservation 61 patients had residual disease in the cavity margin biopsies. Younger age, axillary lymph node status, multi-focal tumours and high grade tumours were significantly correlated with margin involvement. In patients who had clear margins eight patients (2.8%) had developed a local recurrence at follow-up of 55 months (25-89 months). Conclusions: In our hands the use of cavity margin shavings allows us to achieve an acceptable rate of local control. (C) 2003 Elsevier Ltd. All rights reserved.
引用
收藏
页码:644 / 648
页数:5
相关论文
共 29 条
[1]   MARGINS OF LUMPECTOMY FOR BREAST-CANCER [J].
CARTER, D .
HUMAN PATHOLOGY, 1986, 17 (04) :330-332
[2]  
DiBiase SJ, 1998, CANCER, V82, P2212, DOI 10.1002/(SICI)1097-0142(19980601)82:11<2212::AID-CNCR16>3.3.CO
[3]  
2-L
[4]  
England D W, 1994, Eur J Surg Oncol, V20, P425
[5]  
FISHER ER, 1986, CANCER-AM CANCER SOC, V57, P1717, DOI 10.1002/1097-0142(19860501)57:9<1717::AID-CNCR2820570902>3.0.CO
[6]  
2-H
[7]   Randomised controlled trial of conservation therapy for breast cancer: 6-year analysis of the Scottish trial [J].
Forrest, AP ;
Stewart, HJ ;
Everington, D ;
Prescott, RJ ;
McArdle, CS ;
Harnett, AN ;
Smith, DC ;
George, WD .
LANCET, 1996, 348 (9029) :708-713
[8]  
Gage I, 1996, CANCER-AM CANCER SOC, V78, P1921, DOI 10.1002/(SICI)1097-0142(19961101)78:9<1921::AID-CNCR12>3.0.CO
[9]  
2-#
[10]   Conservative surgery in breast cancer. Significance of resection margins [J].
Gennaro, M ;
Ferraris, C ;
Guida, V ;
Tomasic, G ;
Carcangiu, ML ;
Greco, M .
BREAST, 2001, 10 (05) :432-437