A novel magnetic Fe3O4@gold composite nanomaterial: Synthesis and application in regeneration-free immunosensor

被引：19

作者：

Liang, Wenbin ^{[1
]}

Yi, Weijing ^{[1
]}

Li, Yan ^{[2
]}

Zhang, Zhujun ^{[1
]}

Yang, Mingzhen ^{[1
]}

Hu, Chuanmin ^{[1
]}

Chen, An ^{[1
]}

机构：

[1] Third Mil Med Univ, Dept Clin Biochem, Chongqing 400038, Peoples R China

[2] Third Mil Med Univ, Dept Clin Lab Sci, Chongqing 400038, Peoples R China

来源：

MATERIALS LETTERS | 2010年 / 64卷 / 23期

关键词：

Immunosensor; Magnetic materials; Sensors; DIRECT ELECTRON-TRANSFER; FE3O4; NANOPARTICLES; ALPHA-FETOPROTEIN; MULTILAYER FILM; SERUM; HEMOGLOBIN; BIOSENSORS; PROTEINS;

D O I：

10.1016/j.matlet.2010.08.013

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

This paper presents a regeneration-free immunosensor based on a novel magnetic Fe3O4@gold composite nanomaterial, which is able to form a protein/composite nanomaterial due to the stability and biocompatibility of the gold nanomaterial. This enabled simple, effective and controllable detection by immunosensors. In this work, the strategy has been applied to alpha-1-fetoprotein as a model system; however, it could be extended toward other clinically or environmentally interesting biological compounds. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：2616 / 2619

页数：4

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