Cerebellar Cortex and Cerebellar White Matter Volume in Normal Cognition, Mild Cognitive Impairment, and Dementia

被引：4

作者：

Zdanovskis, Nauris ^{[1
,2
]}

Platkajis, Ardis ^{[1
,2
]}

Kostiks, Andrejs ^{[3
]}

Grigorjeva, Olesja ^{[4
]}

Karelis, Guntis ^{[3
]}

机构：

[1] Riga Stradins Univ, Dept Radiol, Dzirciema St 16, LV-1007 Riga, Latvia

[2] Riga East Univ Hosp, Dept Radiol, Hipokrata St 2, LV-1038 Riga, Latvia

[3] Riga East Univ Hosp, Dept Neurosurg & Neurol, Hipokrata St 2, LV-1038 Riga, Latvia

[4] Riga Tech Univ, Dept Comp Control Syst, Kalku St 1, LV-1658 Riga, Latvia

来源：

BRAIN SCIENCES | 2021年 / 11卷 / 09期

关键词：

cerebellum; cortex; volumetry; MRI; dementia; cognitive impairment; white matter; HUMAN CEREBRAL-CORTEX; GEOMETRICALLY ACCURATE; MOTOR; MRI; SEGMENTATION; RELIABILITY; THICKNESS; SYSTEM; AGE;

D O I：

10.3390/brainsci11091134

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

The cerebellum is commonly viewed as a structure that is primarily responsible for the coordination of voluntary movement, gait, posture, and speech. Recent research has shown evidence that the cerebellum is also responsible for cognition. We analyzed 28 participants divided into three groups (9 with normal cognition, 9 with mild cognitive impairment, and 10 with moderate/severe cognitive impairment) based on the Montreal Cognitive Assessment. We analyzed the cerebellar cortex and white matter volume and assessed differences between groups. Participants with normal cognition had higher average values in total cerebellar volume, cerebellar white matter volume, and cerebellar cortex volume in both hemispheres, but by performing the Kruskal-Wallis test, we did not find these values to be statistically significant.

引用

页数：10

共 50 条

[1] The cerebellum and non-motor function: clinical implications [J].