Microwave-assisted efficient synthesis of benzo[4,5]imidazo[1,2-a]pyrimidine derivatives in water under catalyst-free conditions

被引：43
|
作者：
Tu, Shujiang [1 ]
Shao, Qingqing [1 ]
Zhou, Dianxiang [1 ]
Cao, Longji [1 ]
Shi, Feng [1 ]
Li, Chunmei [1 ]
机构：
[1] Xuzhou Normal Univ, Key Lab Biotechnol Med Plant, Dept Chem, Xuzhou 221116, Jiangsu, Peoples R China
来源：
JOURNAL OF HETEROCYCLIC CHEMISTRY | 2007年 / 44卷 / 06期
关键词：
D O I：
10.1002/jhet.5570440625
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Benzo[4,5]imidazo[1,2-a]pyrimidine derivatives were synthesized via the three-component reaction of aldehyde, (beta-dicarbonyl compound and 2-aminobenzimidazole in water under microwave irradiation and without catalyst conditions. The new protocol has the advantages of higher yield, lower cost, reduced environment impact, wider scope and convenient procedure.
引用
收藏
页码：1401 / 1406
页数：6
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