Differentiation potential of adult stem cells

被引：85
作者：
Clarke, D [1 ]
Frisén, J [1 ]
机构：
[1] Karolinska Inst, Med Nobel Inst, Dept Cell & Mol Biol, SE-17177 Stockholm, Sweden
来源：
CURRENT OPINION IN GENETICS & DEVELOPMENT | 2001年 / 11卷 / 05期
关键词：
D O I：
10.1016/S0959-437X(00)00235-5
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
In many different adult tissues, stem cells generate new cells either continuously or in response to injury. Such cells were thought to be limited to generating the types of cells normally present in the tissue where the stem cell resides. However, several different stem-cell populations in the adult have been found recently to be capable of generating additional cell types under certain conditions.
引用
收藏
页码：575 / 580
页数：6
相关论文
共 38 条
  • [21] Marrow stromal cells migrate throughout forebrain and cerebellum, and they differentiate into astrocytes after injection into neonatal mouse brains
    Kopen, GC
    Prockop, DJ
    Phinney, DG
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1999, 96 (19) : 10711 - 10716
  • [22] Multi-organ, multi-lineage engraftment by a single bone marrow-derived stem cell
    Krause, DS
    Theise, ND
    Collector, MI
    Henegariu, O
    Hwang, S
    Gardner, R
    Neutzel, S
    Sharkis, SJ
    [J]. CELL, 2001, 105 (03) : 369 - 377
  • [23] Purified hematopoietic stem cells can differentiate into hepatocytes in vivo
    Lagasse, E
    Connors, H
    Al-Dhalimy, M
    Reitsma, M
    Dohse, M
    Osborne, L
    Wang, X
    Finegold, M
    Weissman, IL
    Grompe, M
    [J]. NATURE MEDICINE, 2000, 6 (11) : 1229 - 1234
  • [24] Turning blood into brain:: Cells bearing neuronal antigens generated in vivo from bone marrow
    Mezey, É
    Chandross, KJ
    Harta, G
    Maki, RA
    McKercher, SR
    [J]. SCIENCE, 2000, 290 (5497) : 1779 - 1782
  • [25] Get to know your stem cells
    Momma, S
    Johansson, CB
    Frisén, J
    [J]. CURRENT OPINION IN NEUROBIOLOGY, 2000, 10 (01) : 45 - 49
  • [26] Regulatory mechanisms in stem cell biology
    Morrison, SJ
    Shah, NM
    Anderson, DJ
    [J]. CELL, 1997, 88 (03) : 287 - 298
  • [27] Groucho-mediated transcriptional repression establishes progenitor cell pattern and neuronal fate in the ventral neural tube
    Muhr, J
    Andersson, E
    Persson, M
    Jessell, TM
    Ericson, J
    [J]. CELL, 2001, 104 (06) : 861 - 873
  • [28] Dedifferentiation of mammalian myotubes induced by msx1
    Odelberg, SJ
    Kollhoff, A
    Keating, MT
    [J]. CELL, 2000, 103 (07) : 1099 - 1109
  • [29] Bone marrow cells regenerate infarcted myocardium
    Orlic, D
    Kajstura, J
    Chimenti, S
    Jakoniuk, I
    Anderson, SM
    Li, BS
    Pickel, J
    McKay, R
    Nadal-Ginard, B
    Bodine, DM
    Leri, A
    Anversa, P
    [J]. NATURE, 2001, 410 (6829) : 701 - 705
  • [30] Bone marrow as a potential source of hepatic oval cells
    Petersen, BE
    Bowen, WC
    Patrene, KD
    Mars, WM
    Sullivan, AK
    Murase, N
    Boggs, SS
    Greenberger, JS
    Goff, JP
    [J]. SCIENCE, 1999, 284 (5417) : 1168 - 1170
1234