Highly stereoselective synthesis of tetrasubstituted alkenes via hydroamination of alkynes and C-H acetoxylation

被引：17

作者：

Liu, Weibing ^{[1
]}

Chen, Cui ^{[1
]}

Zhang, Qing ^{[1
]}

机构：

[1] Univ Petrochem Technol, Sch Chem & Life Sci, Maoming 525000, Peoples R China

来源：

ORGANIC & BIOMOLECULAR CHEMISTRY | 2011年 / 9卷 / 19期

关键词：

O BOND FORMATION; EXPEDITIOUS APPROACH; IODINE; CYCLIZATION; OXIDATION; EFFICIENT; AMIDATION; CHEMISTRY; SCOPE;

D O I：

10.1039/c1ob05958k

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A novel reaction including the sequence of hydroamination of alkynes and subsequent oxidative C-H bond functionalization has been developed in the presence of diacetoxyiodobenzene (DIB). The method allows us to synthesize a wide range of tetrasubstituted (E)-alkenes and provides a potential method to construct densely functionalized carbonyl compounds.

引用

页码：6484 / 6486

页数：3

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