Finding the right KIT inhibitor for advanced systemic mastocytosis

被引：6

作者：

Castells, Mariana ^{[1
,2
]}

Akin, Cem ^{[3
]}

机构：

[1] Brigham & Womens Hosp, Div Allergy & Clin Immunol, 75 Francis St, Boston, MA 02115 USA

[2] Harvard Med Sch, Dept Med, Boston, MA 02115 USA

[3] Univ Michigan, Dept Internal Med, Div Allergy & Immunol, Ann Arbor, MI 48109 USA

来源：

NATURE MEDICINE | 2021年 / 27卷 / 12期

关键词：

CLASSIFICATION; DIAGNOSIS; CELLS;

D O I：

10.1038/s41591-021-01588-z

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Two early-phase clinical trials show impressive response rates and symptom improvement with the selective KIT inhibitor avapritinib, which will provide a much-needed new treatment option for patients.

引用

页码：2081 / 2082

页数：2

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