KCa1.1 channels as therapeutic targets for rheumatoid arthritis

被引:9
|
作者
Beeton, Christine [1 ]
机构
[1] Baylor Coll Med, Dept Mol Physiol & Biophys, Houston, TX 77030 USA
关键词
BK channel; synovial fibroblast; resident joint cells; rheumatoid arthritis; osteoarthritis; regulatory subunit; FIBROBLAST-LIKE SYNOVIOCYTES; K+ CHANNEL; POTASSIUM CHANNELS; LARGE-CONDUCTANCE; EXPRESSION; MECHANISM; PAXILLINE; SUBUNITS; EFFICACY; CELLS;
D O I
10.1080/14728222.2017.1398234
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
引用
收藏
页码:1077 / 1081
页数:5
相关论文
共 50 条
  • [11] Erectile Dysfunction and Altered Contribution of KCa1.1 and KCa2.3 Channels in the Penile Tissue of Type-2 Diabetic db/db Mice
    Comerma-Steffensen, Simon
    Prat-Duran, Judit
    Mogensen, Susie
    Fais, Rafael
    Pinilla, Estefano
    Simonsen, Ulf
    JOURNAL OF SEXUAL MEDICINE, 2022, 19 (05) : 697 - 710
  • [12] Unoprostone activation of BK (Kca1.1) channel splice variants
    Yu, Ling
    Eaton, Amity F.
    Yue, Qiang
    Bao, Hui-Fang
    Ma, He-Ping
    Cuppoletti, John
    Eaton, Douglas C.
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2015, 1848 (11): : 2859 - 2867
  • [13] Different expression of β subunits of the KCa1.1 channel by invasive and non-invasive human fibroblast-like synoviocytes
    Petho, Zoltan
    Tanner, Mark R.
    Tajhya, Rajeev B.
    Huq, Redwan
    Laragione, Teresina
    Panyi, Gyorgy
    Gulko, Percio S.
    Beeton, Christine
    ARTHRITIS RESEARCH & THERAPY, 2016, 18
  • [14] Novel therapeutic targets in rheumatoid arthritis
    Koenders, Marije I.
    van den Berg, Wim B.
    TRENDS IN PHARMACOLOGICAL SCIENCES, 2015, 36 (04) : 189 - 195
  • [15] Future therapeutic targets in rheumatoid arthritis?
    Cheung, Tommy Tsang
    McInnes, Iain B.
    SEMINARS IN IMMUNOPATHOLOGY, 2017, 39 (04) : 487 - 500
  • [16] Mapping the functional expression of auxiliary subunits of KCa1.1 in glioblastoma
    Feher, Adam
    Petho, Zoltan
    Szanto, Tibor G.
    Klekner, Almos
    Tajti, Gabor
    Batta, Gyula
    Hortobagyi, Tibor
    Varga, Zoltan
    Schwab, Albrecht
    Panyi, Gyorgy
    SCIENTIFIC REPORTS, 2022, 12 (01)
  • [17] Therapeutic targets for rheumatoid arthritis: Progress and promises
    Alghasham, Abdullah
    Rasheed, Zafar
    AUTOIMMUNITY, 2014, 47 (02) : 77 - 94
  • [18] Promising Therapeutic Targets for Treatment of Rheumatoid Arthritis
    Huang, Jie
    Fu, Xuekun
    Chen, Xinxin
    Li, Zheng
    Huang, Yuhong
    Liang, Chao
    FRONTIERS IN IMMUNOLOGY, 2021, 12
  • [19] The secretory KCa1.1 channel localises to crypts of distal mouse colon: functional and molecular evidence
    Sorensen, Mads V.
    Strandsby, Anne B.
    Larsen, Casper K.
    Praetorius, Helle A.
    Leipziger, Jens
    PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY, 2011, 462 (05): : 745 - 752
  • [20] Calcium channels: the potential therapeutic targets for inflammatory bone destruction of rheumatoid arthritis
    Robin Park
    Jong Dae Ji
    Inflammation Research, 2016, 65 : 347 - 354