Increased Social Support Reduces the Incidence of Motoric Cognitive Risk Syndrome

被引:13
作者
Felix, Nicole [1 ]
Ayers, Emmeline [2 ]
Verghese, Joe [1 ,2 ]
Blumen, Helena M. [1 ,2 ]
机构
[1] Albert Einstein Coll Med, Dept Med, 1225 Morris Pk Ave,Van Etten Bldg,Room 319, Bronx, NY 10461 USA
[2] Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
关键词
Predementia; Preclinical dementia; Slow gait; Subjective cognitive complaint; ALZHEIMERS-DISEASE; IMPAIRMENT; DEMENTIA; DECLINE; RBANS; LIFE;
D O I
10.1093/geroni/igac048
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
Background and Objectives The motoric cognitive risk syndrome (MCR) is a predementia syndrome characterized by slow gait and cognitive complaint. The relationship between MCR and social support-a potentially modifiable risk factor of dementia-is currently unknown. The current study aimed to determine whether MCR incidence varies as a function of social support in aging. Research Design and Methods We examined MCR incidence in 506 community-dwelling older adults (M Age 76.59; 57.3% female) without MCR or dementia at baseline. We quantified perceived levels of social support with the Medical Outcomes Study Social Support Survey, incorporating four different categories of support: (a) emotional/informational support, (b) tangible support, (c) affectionate support, and (d) positive social interactions. We used Cox regression analyses, adjusted for age, sex, race/ethnicity, education, marital status, comorbidities, and global cognition, to estimate hazard ratios (aHR) with 95% confidence intervals (CIs). Results Over a median follow-up time of 2.5 years (range = 1-7 years), 38 participants (9.8%) developed MCR. Increased tangible support decreased the risk of MCR by 30% (aHR: 0.70, 95% CI: 0.53-0.92, p = .011). Increased overall social support decreased the risk of MCR by 33% (aHR: 0.67, 95% CI: 0.46-0.98, p = .038). Other subcategories of social support were not associated with a decreased risk of MCR (p > .05). Discussion and Implications Higher levels of tangible social support, as well as overall social support, were associated with reduced risk for MCR in older adults. Increasing social support may be a promising avenue of intervention for reducing the risk of MCR, dementia, and other forms of cognitive decline.
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页数:8
相关论文
共 45 条
[1]   Effects of social network diversity on mortality, cognition and physical function in the elderly: a longitudinal analysis of the Chicago Health and Aging Project (CHAP) [J].
Ali, Talha ;
Nilsson, Charlotte Juul ;
Weuve, Jennifer ;
Rajan, Kumar B. ;
de Leon, Carlos F. Mendes .
JOURNAL OF EPIDEMIOLOGY AND COMMUNITY HEALTH, 2018, 72 (11) :990-996
[2]  
Antonucci T., 1990, HDB AGING SOCIAL SCI, P272
[3]   The Effect of Personality Traits on Risk of Incident Pre-dementia Syndromes [J].
Ayers, Emmeline ;
Gulley, Emma ;
Verghese, Joe .
JOURNAL OF THE AMERICAN GERIATRICS SOCIETY, 2020, 68 (07) :1554-1559
[4]   Social resources and cognitive decline in a population of older African Americans and whites [J].
Barnes, LL ;
de Leon, CFM ;
Wilson, RS ;
Bienias, JL ;
Evans, DA .
NEUROLOGY, 2004, 63 (12) :2322-2326
[5]   Social disengagement and incident cognitive decline in community-dwelling elderly persons [J].
Bassuk, SS ;
Glass, TA ;
Berkman, LF .
ANNALS OF INTERNAL MEDICINE, 1999, 131 (03) :165-+
[6]   Association of Motoric Cognitive Risk Syndrome with Cardiovascular Disease and Risk Factors: Results from an Original Study and Meta-Analysis [J].
Beauchet, Olivier ;
Sekhona, Harmehr ;
Barden, John ;
Liu-Ambrose, Teresa ;
Chester, Victoria L. ;
Szturm, Tony ;
Grenier, Sebastien ;
Leonard, Guillaume ;
Bherer, Louis ;
Allali, Gilles .
JOURNAL OF ALZHEIMERS DISEASE, 2018, 64 (03) :875-887
[7]   The effect of social networks on the relation between Alzheimer's disease pathology and level of cognitive function in old people: a longitudinal cohort study [J].
Bennett, DA ;
Schneider, JA ;
Tang, YX ;
Arnold, SE ;
Wilson, RS .
LANCET NEUROLOGY, 2006, 5 (05) :406-412
[8]   Social prescribing: less rhetoric and more reality. A systematic review of the evidence [J].
Bickerdike, Liz ;
Booth, Alison ;
Wilson, Paul M. ;
Farley, Kate ;
Wright, Kath .
BMJ OPEN, 2017, 7 (04)
[9]   Cortical Thickness, Volume, and Surface Area in the Motoric Cognitive Risk Syndrome [J].
Blumen, Helena M. ;
Schwartz, Emily ;
Allali, Gilles ;
Beauchet, Olivier ;
Callisaya, Michele ;
Doi, Takehiko ;
Shimada, Hiroyuki ;
Srikanth, Velandai ;
Verghese, Joe .
JOURNAL OF ALZHEIMERS DISEASE, 2021, 81 (02) :651-665
[10]   Gray matter volume covariance networks associated with social networks in older adults [J].
Blumen, Helena M. ;
Verghese, Joe .
SOCIAL NEUROSCIENCE, 2019, 14 (05) :559-570