Is age of menarche among school girls related to breastfeeding during infancy?

Objectives Breastfeeding has been linked to various disease conditions in adulthood. Age of menarche has been proposed to be an intermediary factor on the life-course path to these disease conditions, but the link between breastfeeding and age of menarche remains under debate. This study aimed to investigate the association between age of menarche and breastfeeding during infancy. Methods Results A cross-sectional study was conducted in which 775 female high school students were randomly selected from private and public high schools in all provinces in Kuwait. Data on age of menarche were collected by self-administered questionnaires from the students, while data on breastfeeding were collected from their mothers through telephone interviews. Multiple linear regression was used to investigate the association between breastfeeding and age of menarche after adjusting for potential confounders. Of the study group 496 mothers responded to the telephone interview. Duration of breastfeeding was not significantly associated with age of menarche before or after adjusting for potential confounders (P = .279 and P = .124 for crude and fully adjusted model, respectively). Similarly, no significant association was found between type of breastfeeding during the first four months of life and age of menarche before or after adjusting for potential confounders (P = .949 and P = .398 for crude and fully adjusted model, respectively). Conclusion No significant association was found between age of menarche and breastfeeding during infancy, which may suggest that the link between breastfeeding and disease conditions in adulthood is not necessarily mediated through age of menarche.