Could peptide-decorated nanoparticles provide an improved approach for treating pregnancy complications?

被引:13
作者
Harris, Lynda K. [1 ,2 ,3 ]
机构
[1] Univ Manchester, Manchester Pharm Sch, Stopford Bldg,Oxford Rd, Manchester M13 9PT, Lancs, England
[2] Univ Manchester, Maternal & Fetal Hlth Res Ctr, Inst Human Dev, Oxford Rd, Manchester M13 9WL, Lancs, England
[3] St Marys Hosp, Acad Hlth Sci Ctr, Oxford Rd, Manchester M13 9WL, Lancs, England
基金
英国生物技术与生命科学研究理事会;
关键词
drug delivery; homing peptides; liposomes; nanoparticles; obstetrics; placenta; pregnancy; targeting; DRUG-DELIVERY; FETAL-GROWTH;
D O I
10.2217/nnm-2016-0234
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
引用
收藏
页码:2235 / 2238
页数:4
相关论文
共 20 条
[1]   Development of Non-Viral, Trophoblast-Specific Gene Delivery for Placental Therapy [J].
Abd Ellah, Noura ;
Taylor, Leeanne ;
Troja, Weston ;
Owens, Kathryn ;
Ayres, Neil ;
Pauletti, Giovanni ;
Jones, Helen .
PLOS ONE, 2015, 10 (10)
[2]   Effect of surface charge of small unilamellar liposomes on uptake and transfer of carboxyfluorescein across the perfused human term placenta [J].
Bajoria, R ;
Contractor, SF .
PEDIATRIC RESEARCH, 1997, 42 (04) :520-527
[3]  
Beards F, 2015, REPROD SCI, V22, p77A
[4]   Uteroplacental Adenovirus Vascular Endothelial Growth Factor Gene Therapy Increases Fetal Growth Velocity in Growth-Restricted Sheep Pregnancies [J].
Carr, David J. ;
Wallace, Jacqueline M. ;
Aitken, Raymond P. ;
Milne, John S. ;
Mehta, Vedanta ;
Martin, John F. ;
Zachary, Ian C. ;
Peebles, Donald M. ;
David, Anna L. .
HUMAN GENE THERAPY, 2014, 25 (04) :375-384
[5]   Cardiovascular Risk Factors in Children and Young Adults Born to Preeclamptic Pregnancies: A Systematic Review [J].
Davis, Esther Frances ;
Lazdam, Merzaka ;
Lewandowski, Adam James ;
Worton, Stephanie Anne ;
Kelly, Brenda ;
Kenworthy, Yvonne ;
Adwani, Satish ;
Wilkinson, Andrew R. ;
McCormick, Kenny ;
Sargent, Ian ;
Redman, Christopher ;
Leeson, Paul .
PEDIATRICS, 2012, 129 (06) :E1552-E1561
[6]   Market failure and the poverty of new drugs in maternal health [J].
Fisk, Nicholas M. ;
Atun, Rifat .
PLOS MEDICINE, 2008, 5 (01) :22-28
[7]   Statins are detrimental to human placental development and function; use of statins during early pregnancy is inadvisable [J].
Forbes, Karen ;
Hurst, Lucy M. ;
Aplin, John D. ;
Westwood, Melissa ;
Gibson, J. Martin .
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE, 2008, 12 (6A) :2295-2296
[8]   Effect of in utero and early-life conditions on adult health and disease [J].
Gluckman, Peter D. ;
Hanson, Mark A. ;
Cooper, Cyrus ;
Thornburg, Kent L. .
NEW ENGLAND JOURNAL OF MEDICINE, 2008, 359 (01) :61-73
[9]  
Holtan SG, 2009, MAYO CLIN PROC, V84, P985, DOI 10.1016/S0025-6196(11)60669-1
[10]   Targeted Nanoparticle Delivery of Doxorubicin Into Placental Tissues to Treat Ectopic Pregnancies [J].
Kaitu'u-Lino, Tu'uhevaha J. ;
Pattison, Scott ;
Ye, Louie ;
Tuohey, Laura ;
Sluka, Pavel ;
MacDiarmid, Jennifer ;
Brahmbhatt, Himanshu ;
Johns, Terrence ;
Horne, Andrew W. ;
Brown, Jeremy ;
Tong, Stephen .
ENDOCRINOLOGY, 2013, 154 (02) :911-919