Csp3-Csp2 Palladium-Catalyzed Cross-Coupling Reaction of Trialkylbismuth Reagents with Aryl, Heteroaryl, and Vinyl Halides and Triflates

被引：18
|
作者：
Gagnon, Alexandre [1 ]
Albert, Vincent [1 ]
Duplessis, Martin [1 ]
机构：
[1] Boehringer Ingelheim Canada Ltd, Res & Dev, Laval, PQ H7S 2G5, Canada
来源：
SYNLETT | 2010年 / 19期
关键词：
cross-coupling; organometallic reagents; palladium; halides; catalysis; DEFICIENT OLEFIN LIGAND; ORGANOBISMUTH REAGENTS; ALKYLZINC REAGENTS; ROOM-TEMPERATURE; BROMIDES; IODIDES; TRIARYLBISMUTHS; DIALKOXIDES; CHEMISTRY; CHLORIDES;
D O I：
10.1055/s-0030-1259023
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
The palladium-catalyzed cross-coupling reaction of trialkylbismuth reagents with aryl and heteroaryl halides and triflates is reported. Moderate to good yields were obtained for the transfer of primary alkyl groups. The reaction tolerates numerous functional groups on the electrophilic and nucleophilic partners. The cross-coupling of alpha-bromostyrene with tris(1,3-dioxan-2-ylethyl) bismuth is also reported.
引用
收藏
页码：2936 / 2940
页数：5
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