Value of ultrasound combined with MRI in the diagnosis of primary and recurrent hepatocellular carcinoma

被引:5
作者
Ji, Xiaoli [1 ]
Zhou, Shisheng [2 ]
Yang, Peng [3 ]
Liu, Faqin [4 ]
Li, Yan [4 ]
Li, Hong [5 ]
机构
[1] Qingdao Women & Childrens Hosp, Dept Special Inspect Ultrasound Obstet & Gynecol, Qingdao 266034, Shandong, Peoples R China
[2] Yantaishan Hosp, Dept Ultrasound, Yantai 264000, Shandong, Peoples R China
[3] Peoples Hosp Zhangqiu Area, Adm Dept Outpatient, Jinan 250200, Shandong, Peoples R China
[4] Peoples Hosp Zhangqiu Area, Dept Operating Room, Jinan 250200, Shandong, Peoples R China
[5] Jining 1 Peoples Hosp, Dept Ultrasound, 6 Jiankang Rd, Jining 272111, Shandong, Peoples R China
关键词
primary hepatocellular carcinoma; magnetic resonance imaging; ultrasound; recurrent hepatocellular carcinoma; diagnostic value; LIVER-CANCER; TRANSPLANTATION; ENHANCEMENT; PROBE; DRUG;
D O I
10.3892/ol.2019.10945
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Ultrasound (US) combined with magnetic resonance imaging (MRI) in the diagnosis of primary hepatocellular carcinoma (PHCC) and recurrent hepatocellular carcinoma (RHCC) were compared. The clinical data of 329 patients with hepatocellular carcinoma (HCC) admitted to Qingdao Women and Children's Hospital from June 2015 to December 2017 were collected. One hundred and sixty patients with PHCC were regarded as the PHCC group, and the other 169 patients with RHCC were regarded as the RHCC group. US and MRI were used in the imaging diagnosis of both groups and the results of US combined with MRI, US, and MRI alone were compared. The lesion size in the PHCC group was significantly higher than that in the RHCC group (P<0.05). The MRI fast-in and fast-out rates of the two groups were significantly higher than those of the other three methods (P<0.05). The coincidence rate of MRI in the two groups was higher than that of computed tomography (CT), US, and US combined with MRI (P<0.05). The coincidence rates of CT, US, MRI, and US combined with MRI in PHCC group were significantly higher than those in RHCC group. In PHCC group, MRI was superior to the other methods in the detection of micro HCC (P<0.05). In RHCC group, MRI was significantly better than US in the detection of micro HCC (P<0.05). The sensitivity, specificity, positive predictive value and negative predictive value of MRI were significantly better than the other three methods (P<0.05). MRI alone has the best diagnostic efficacy for micro HCC-type lesions. The diagnostic efficacy of MRI, US, CT, and US combined with MRI in PHCC was better than those in RHCC. In addition to imaging examination, the diagnosis of RHCC should be combined with other indicators for comprehensive diagnosis.
引用
收藏
页码:6180 / 6186
页数:7
相关论文
共 25 条
[1]   Evidence-Based Diagnosis, Staging, and Treatment of Patients With Hepatocellular Carcinoma [J].
Bruix, Jordi ;
Reig, Maria ;
Sherman, Morris .
GASTROENTEROLOGY, 2016, 150 (04) :835-853
[2]   Theranostic imaging of liver cancer using targeted optical/MRI dual-modal probes [J].
Chen, Qingshan ;
Shang, Wenting ;
Zeng, Chaoting ;
Wang, Kun ;
Liang, Xiaoyuan ;
Chi, Chongwei ;
Liang, Xiao ;
Yang, Jian ;
Fang, Chihua ;
Tian, Jie .
ONCOTARGET, 2017, 8 (20) :32741-32751
[3]   Practice guidelines for the pathological diagnosis of primary liver cancer: 2015 update [J].
Cong, Wen-Ming ;
Bu, Hong ;
Chen, Jie ;
Dong, Hui ;
Zhu, Yu-Yao ;
Feng, Long-Hai ;
Chen, Jun .
WORLD JOURNAL OF GASTROENTEROLOGY, 2016, 22 (42) :9279-9287
[4]  
Dumitrescu CI, 2013, MED ULTRASON, V15, P261
[5]   Recurrence of hepatocellular carcinoma after liver transplantation [J].
Escartin, A. ;
Sapisochin, G. ;
Bilbao, I. ;
Vilallonga, R. ;
Bueno, J. ;
Castells, L. ;
Dopazo, C. ;
Castro, E. ;
Caralt, M. ;
Balsells, J. .
TRANSPLANTATION PROCEEDINGS, 2007, 39 (07) :2308-2310
[6]   Enhancement pattern of small hepatocellular carcinoma (HCC) at contrast-enhanced US (CEUS), MDCT, and MRI: Intermodality agreement and comparison of diagnostic sensitivity between 2005 and 2010 American Association for the Study of Liver Diseases (AASLD) guidelines [J].
Furlan, Alessandro ;
Marin, Daniele ;
Cabassa, Paolo ;
Taibbi, Adele ;
Brunelli, Elena ;
Agnello, Francesco ;
Lagalla, Roberto ;
Brancatelli, Giuseppe .
EUROPEAN JOURNAL OF RADIOLOGY, 2012, 81 (09) :2099-2105
[7]   Enhancement of anti-tumor effects of 5-fluorouracil on hepatocellular carcinoma by low-intensity ultrasound [J].
Hu, Zheng ;
Lv, Guixiang ;
Li, Yongning ;
Li, Enze ;
Li, Haixia ;
Zhou, Qi ;
Yang, Bin ;
Cao, Wenwu .
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH, 2016, 35
[8]   Salvage Liver Transplantation Is a Reasonable Option for Selected Patients Who Have Recurrent Hepatocellular Carcinoma after Liver Resection [J].
Hu, Zhenhua ;
Zhou, Jie ;
Xu, Xiaofeng ;
Li, Zhiwei ;
Zhou, Lin ;
Wu, Jian ;
Zhang, Min ;
Zheng, Shusen .
PLOS ONE, 2012, 7 (05)
[9]   Efficacy of sorafenib after liver transplantation in patients with primary hepatic carcinoma exceeding the Milan criteria: a preliminary study (Publication with Expression of Concern. See vol. 13, pg. 3289, 2020) [J].
Huang, Lei ;
Li, Guang-ming ;
Zhu, Ji-ye ;
Li, Zhao ;
Li, Tao ;
Leng, Xi-sheng .
ONCOTARGETS AND THERAPY, 2012, 5 :457-462
[10]   Impact of diffusion-weighted MR imaging on the characterization of small hepatocellular carcinoma in the cirrhotic liver [J].
Le Moigne, Francois ;
Durieux, Marion ;
Bancel, Brigitte ;
Boublay, Nawele ;
Boussel, Loic ;
Ducerf, Christian ;
Berthezene, Yves ;
Rode, Agnes .
MAGNETIC RESONANCE IMAGING, 2012, 30 (05) :656-665