Analysis of the antiepileptic drug keppra by capillary electrophoresis

被引：40

作者：

Shihabi, ZK ^{[1
]}

Oles, K

Hinsdale, M

机构：

[1] Wake Forest Univ, Sch Med, Dept Pathol, Winston Salem, NC 27157 USA

[2] Wake Forest Univ, Sch Med, Dept Internal Med, Winston Salem, NC 27157 USA

来源：

JOURNAL OF CHROMATOGRAPHY A | 2003年 / 1004卷 / 1-2期

关键词：

pharmaceutical analysis; keppra; levetiracetam;

D O I：

10.1016/S0021-9673(03)00716-7

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple and rapid method for determination of the new antiepileptic drug keppra (levetiracetam) by capillary electrophoresis in borate buffer containing sodium dodecyl sulfate is described. The serum was injected without any treatment. The method compared well to high performance liquid chromatography. The mean of keppra in the serum of 35 patients was 25 mg/l (range 7-77 mg/l). (C) 2003 Elsevier B.V. All rights reserved.

引用

页码：9 / 12

页数：4

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