Cognitive impairment in pediatric multiple sclerosis

被引：19

作者：

Ghezzi, A. ^{[1
]}

Goretti, B. ^{[2
]}

Portaccio, E. ^{[2
]}

Roscio, M. ^{[1
]}

Amato, M. P. ^{[2
]}

机构：

[1] Azienda Osped S Antonio Abate di Gallarate, Ctr Studi Sclerosi Multipla, I-21013 Gallarate, Italy

[2] Univ Florence, Dept Neurol, Florence, Italy

来源：

NEUROLOGICAL SCIENCES | 2010年 / 31卷

关键词：

Cognitive impairment; Childhood; Adolescence; Multiple sclerosis; WHITE-MATTER; CHILDREN; CHILDHOOD; FEATURES; ONSET; GRAY; MS;

D O I：

10.1007/s10072-010-0437-8

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Cognitive impairment has been recently recognized in patients with pediatric multiple sclerosis in more than 30% of cases. Altered functions with variable frequency are: attention, language (receptive, verbal fluency, naming), visual-spatial and motor functions, spatial memory, executive functions and abstract reasoning. Fatigue and affective disorders are associated, but not correlated with cognitive impairment. The frequency and severity of cognitive impairment increase with time. Cognitive impairment has a negative impact on patient's life limiting social, academic and recreational activities.

引用

页码：215 / 218

页数：4

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