Scrotal cancer: incidence, survival and second primary tumours in the Netherlands since 1989

被引：25

作者：

Verhoeven, R. H. A. ^{[1
]}

Louwman, W. J. ^{[1
]}

Koldewijn, E. L. ^{[2
]}

Demeyere, T. B. J. ^{[3
]}

Coebergh, J. W. W. ^{[1
,4
]}

机构：

[1] Comprehens Canc Ctr S, Dept Res, Eindhoven Canc Registry, NL-5600 AE Eindhoven, Netherlands

[2] Catharina Hosp, Dept Urol, NL-5602 ZA Eindhoven, Netherlands

[3] PAMM Reg Lab Pathol & Microbiol, NL-5500 AA Veldhoven, Netherlands

[4] Erasmus MC, Dept Publ Hlth, NL-3000 CA Rotterdam, Netherlands

来源：

BRITISH JOURNAL OF CANCER | 2010年 / 103卷 / 09期

关键词：

scrotum; neoplasms; incidence; survival rate; second primary; carcinoma; squamous cell; SKIN-CANCER; UNITED-STATES; CARCINOMA; RISK; EXPERIENCE; MORTALITY; PSORIASIS; ENGLAND;

D O I：

10.1038/sj.bjc.6605914

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

BACKGROUND: Since the 1970s there have been few epidemiological studies of scrotal cancer. We report on the descriptive epidemiology of scrotal cancer in the Netherlands. METHODS: Data on all scrotal cancer patients were obtained from the Netherlands Cancer Registry (NCR) in the period 1989-2006 and age-standardised incidence rates were calculated also according to histology and stage. Relative survival was calculated and multiple primary tumours were studied. RESULTS: The overall incidence rate varied around 1.5 per 1 000 000 person-years, most frequently being squamous cell carcinoma (27%), basal cell carcinoma (19%) and Bowen's disease (15%). Overall 5-year relative survival was 82%, being 77% and 95% for patients with squamous and basal cell carcinoma, respectively. In all, 18% of the patients were diagnosed with a second primary tumour. CONCLUSION: The incidence rate of scrotal cancer did not decrease, although this was expected; affected patients might benefit from regular checkups for possible new cancers. British Journal of Cancer (2010) 103, 1462-1466. doi: 10.1038/sj.bjc.6605914 www.bjcancer.com Published online 28 September 2010 (C) 2010 Cancer Research UK

引用

页码：1462 / 1466

页数：5

共 35 条

[1] SQUAMOUS-CELL CARCINOMA OF THE SCROTUM - LONG-TERM FOLLOW-UP OF 14 PATIENTS [J].

ANDREWS, PE ;

FARROW, GM ;

OESTERLING, JE .

JOURNAL OF UROLOGY, 1991, 146 (05) :1299-1304

[2]

[Anonymous], 2013, International Classification of disease for Oncology

[3] Mortality from scrotal cancer in metal machinists in England and Wales, 1979-80 and 1982-90 [J].

Coggon, D ;

Inskip, H ;

Winter, P ;

Pannett, B .

OCCUPATIONAL MEDICINE-OXFORD, 1996, 46 (01) :69-70

[4]

de Vries E, 2006, Ned Tijdschr Geneeskd, V150, P1108

[5]

DOLL R, 1972, BRIT J IND MED, V29, P394

[6] INCIDENCE OF MALE GENITAL SKIN TUMORS - LACK OF INCREASE IN THE UNITED-STATES [J].

GOLDOFT, MJ ;

WEISS, NS .

CANCER CAUSES & CONTROL, 1992, 3 (01) :91-93

[7] Cumulation of TP53 mutations and p16INK4A/p15INK4B homozygous deletions in human papilloma virus type 16 positive scrotal cancer [J].

Güran, S ;

Pak, I .

CANCER GENETICS AND CYTOGENETICS, 1999, 109 (02) :108-113

[8] A COMPUTER-PROGRAM PACKAGE FOR RELATIVE SURVIVAL ANALYSIS [J].

HAKULINEN, T ;

ABEYWICKRAMA, KH .

COMPUTER PROGRAMS IN BIOMEDICINE, 1985, 19 (2-3) :197-207

[9]

Heller I., 1930, Journal of Industrial Hygiene, V12, P169

[10]

HENRY SA, 1947, BRIT MED BULL, V4, P389

← 1 2 3 4 →