Parasitic infection leads to decline in hemolymph sugar levels in honeybee foragers

Parasites by drawing nutrition from their hosts can exert an energetic stress on them. Honeybee foragers with their high metabolic demand due to flight are especially prone to such a stress when they are infected. We hypothesized that infection by the microsporidian gut parasite Nosema ceranae can lower the hemolymph sugar level of an individual forager and uncouple its energetic state from its normally tight correlation with the colony energetic state. We support our hypothesis by showing that free-flying foragers that are infected have lower trehalose levels than uninfected ones but the two do not differ in their trehalose levels when fed until satiation. The trehalose level of infected bees was also found to decline at a faster rate while their glucose level is maintained at a quantity comparable to uninfected bees. These results suggest that infected foragers have lower flying ability and the intriguing possibility that the carbohydrate levels of an individual bee can act as a modulator of its foraging behavior, independent of social cues such as colony demand for nectar. We discuss the importance of such pathophysiological changes on foraging behavior in the context of the recently observed colony collapses. (C) 2010 Elsevier Ltd. All rights reserved.