Discovery and structure-activity relationship (SAR) of novel pyridylureas as potent antibacterial agents

被引：0
|
作者：
Bist, Shanta [1 ]
Basarab, Greg [1 ]
Manchester, John [1 ]
Sherer, Brian [2 ]
机构：
[1] AstraZeneca R&D Boston, Waltham, MA 02451 USA
[2] EMD Serono Res & Dev Inst, Billerica, MA 01821 USA
来源：
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | 2014年 / 247卷
关键词：
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
107-MEDI
引用
收藏
页数：1
相关论文
共 50 条
  • [31] Synthetic and natural coumarins as potent anticonvulsant agents: A review with structure-activity relationship
    Keri, Rangappa S.
    Budagumpi, Srinivasa
    Somappa, Sasidhar Balappa
    JOURNAL OF CLINICAL PHARMACY AND THERAPEUTICS, 2022, 47 (07) : 915 - 931
  • [32] Structure-activity relationship study of cationic carbosilane dendritic systems as antibacterial agents
    Fuentes-Paniagua, Elena
    Sanchez-Nieves, Javier
    Hernandez-Ros, Jose M.
    Fernandez-Ezequiel, Alba
    Soliveri, Juan
    Copa-Patino, Jose L.
    Gomez, Rafael
    Javier de la Mata, F.
    RSC ADVANCES, 2016, 6 (09) : 7022 - 7033
  • [33] Evaluation of withaferin-A and analogues as antibacterial agents: Structure-activity relationship study
    Moujir, L.
    Araujo, L.
    Llanos, G.
    Jimenez, I
    Bazzocchi, I
    PLANTA MEDICA, 2014, 80 (16) : 1492 - 1492
  • [34] Synthesis and structure-activity relationships of 2-pyridones: A novel series of potent DNA gyrase inhibitors as antibacterial agents
    Li, Q
    Chu, DTW
    Claiborne, A
    Cooper, CS
    Lee, CM
    Raye, K
    Berst, KB
    Donner, P
    Wang, WB
    Hasvold, L
    Fung, A
    Ma, ZK
    Tufano, M
    Flamm, R
    Shen, LL
    Baranowski, J
    Nilius, A
    Alder, J
    Meulbroek, J
    Marsh, K
    Crowell, D
    Hui, YH
    Seif, L
    Melcher, LM
    Henry, R
    Spanton, S
    Faghih, R
    Klein, LL
    Tanaka, SK
    Plattner, JJ
    JOURNAL OF MEDICINAL CHEMISTRY, 1996, 39 (16) : 3070 - 3088
  • [35] STRUCTURE-ACTIVITY RELATIONSHIP (SAR) OF CURARIZING DRUGS
    LOEWE, S
    HARVEY, SC
    JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS, 1951, 101 (01): : 23 - 23
  • [36] PubChem structure-activity relationship (SAR) clusters
    Kim, Sunghwan
    Han, Lianyi
    Yu, Bo
    Haehnke, Volker D.
    Bolton, Evan E.
    Bryant, Stephen H.
    JOURNAL OF CHEMINFORMATICS, 2015, 7
  • [37] PubChem structure-activity relationship (SAR) clusters
    Kim, Sunghwan
    Han, Lianyi
    Bolton, Evan E.
    Bryant, Stephen H.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2013, 246
  • [38] Synthesis and structure-activity relationship of carbazole sulfonamides as a novel class of potent antimitotic agents against solid tumors
    Hu, Lai-xing
    Li, Zuo-rong
    Jiang, Jian-dong
    Boykin, David W.
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2006, 231
  • [39] Discovery, Optimization, and Structure-Activity Relationship Study of Novel and Potent RSK4 Inhibitors as Promising Agents for the Treatment of Esophageal Squamous Cell Carcinoma
    Yuan, Yuan
    Xu, Junpeng
    Jiang, Lei
    Yu, Kangjie
    Ge, Yuanyuan
    Li, Mingyang
    He, Huan
    Niu, Qiqi
    Shi, Xiayu
    Fan, Linni
    Chen, Zhuo
    Zhao, Zhenjiang
    Li, Shiliang
    Xu, Yufang
    Wang, Zhe
    Li, Honglin
    JOURNAL OF MEDICINAL CHEMISTRY, 2021, 64 (18) : 13572 - 13587
  • [40] Structure-activity relationship (SAR) studies on oxazolidinone antibacterial agents. 1. Conversion of 5-substituent on oxazolidinone
    Tokuyama, R
    Takahashi, Y
    Tomita, Y
    Suzuki, T
    Yoshida, T
    Iwasaki, N
    Kado, N
    Okezaki, E
    Nagata, O
    CHEMICAL & PHARMACEUTICAL BULLETIN, 2001, 49 (04) : 347 - 352
12345