Prevalence and antimicrobial resistance of Campylobacter isolates in broilers from China

被引：122

作者：

Chen, Xia ^{[1
]}

Naren, Gao-Wa ^{[1
]}

Wu, Cong-Ming ^{[1
]}

Wang, Yang ^{[1
]}

Dai, Lei ^{[1
]}

Xia, Li-Ning ^{[1
]}

Luo, Peng-Jie ^{[2
]}

Zhang, Qijing ^{[3
]}

Shen, Jian-Zhong ^{[1
]}

机构：

[1] China Agr Univ, Coll Vet Med, Dept Vet Pharmacol & Toxicol, Natl Reference Lab Vet Drug Residue,Key Lab Dev &, Beijing 100193, Peoples R China

[2] Chinese Ctr Dis Control & Prevent, Natl Inst Nutr & Food Safety, Beijing 100021, Peoples R China

[3] Iowa State Univ, Coll Vet Med, Dept Vet Microbiol & Prevent Med, Ames, IA 50011 USA

来源：

VETERINARY MICROBIOLOGY | 2010年 / 144卷 / 1-2期

关键词：

Campylobacter jejuni; Campylobacter coli; Isolation rate; Antimicrobial resistance; ANTIBIOTIC-RESISTANCE; FLUOROQUINOLONE RESISTANCE; CIPROFLOXACIN RESISTANCE; MACROLIDE RESISTANCE; JEJUNI INFECTIONS; DRUG-RESISTANCE; DNA MICROARRAY; COLI; CHICKENS; POULTRY;

D O I：

10.1016/j.vetmic.2009.12.035

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The prevalence and antimicrobial resistance of Campylobacter spp. in broiler chickens were determined in Shandong Province, China. In total, 275 Campylobacter isolates were obtained from 767 broiler cecal samples, including 208 Campylobacter jejuni, 53 Campylobacter colt, and 14 unidentified Campylobacter isolates. Minimal inhibitory concentrations of 11 antimicrobial agents were determined using the agar dilution method recommended by CLSI. More than 98% of the tested Campylobacter isolates were resistant to quinolones (nalidixic acid, ciprofloxacin and enrofloxacin) and tetracyclines (tetracycline and doxycycline). The C. jejuni isolates also exhibited a high rate of resistance to phenicol antibiotics and a moderate rate of resistance to macrolides and gentamicin. On the contrary, the C. colt isolates showed a high-level resistance to macrolides and gentamicin and little resistance to phenicol antibiotics. The vast majority of the Campylobacter isolates were classified as multidrug resistant. These findings reveal a broad extent of antimicrobial resistance in Campylobacter isolates from poultry in China and underline the need for prudent use of antibiotics in poultry production to minimize the spread of antibiotic resistant Campylobacter. (C) 2010 Elsevier B.V. All rights reserved.

引用

页码：133 / 139

页数：7

共 29 条

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