Grappling with the Androgen Receptor: A New Approach for Treating Advanced Prostate Cancer

被引：2

作者：

Thompson, Timothy C. ^{[1
]}

机构：

[1] Univ Texas MD Anderson Canc Ctr, Dept Genitourinary Med Oncol, Houston, TX 77030 USA

来源：

CANCER CELL | 2010年 / 17卷 / 06期

关键词：

D O I：

10.1016/j.ccr.2010.05.018

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

In this issue of Cancer Cell, Andersen et al. report on a small molecule that interacts with and blocks trans-activation of the androgen receptor amino-terminal domain. This agent can overcome the shortcomings of clinically used antiandrogens, an important advance in the development of effective therapy for advanced prostate cancer.

引用

页码：525 / 526

页数：2

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