Interferon-β treatment in patients with childhood onset multiple sclerosis

被引：86
作者：
Mikaelloff, Y
Moreau, T
Debouverie, M
Pelletier, J
Lebrun, C
Gout, O
Pedespan, JM
Van Hulle, C
Vermersch, P
Ponsot, G
机构：
[1] Hop St Vincent de Paul, Serv Neurol Pediat, Dept Neuropediat, F-75674 Paris 14, France
[2] Univ Hosp, Bordeaux, France
[3] Univ Rouen, Hosp, Rouen, France
[4] Univ Dijon, Hosp, Dept Neurol, F-21004 Dijon, France
[5] Nancy Univ Hosp, Nancy, France
[6] Univ Hosp, Marseille, France
[7] Univ Nice, Hosp, Nice, France
[8] Hop La Pitie Salpetriere, Paris, France
[9] Univ Lille, Hosp, Lille, France
来源：
JOURNAL OF PEDIATRICS | 2001年 / 139卷 / 03期
关键词：
D O I：
10.1067/mpd.2001.117004
中图分类号：
R72 [儿科学];
学科分类号：
100202 ;
摘要：
We present a report of the use of interferon-beta before 18 years of age in 16 patients with childhood-onset multiple sclerosis. This study demonstrated that the treatment is safe and well tolerated.
引用
收藏
页码：443 / 446
页数：4
相关论文
共 11 条
  • [1] INTERFERON BETA-1B IS EFFECTIVE IN RELAPSING-REMITTING MULTIPLE-SCLEROSIS - CLINICAL-RESULTS OF A MULTICENTER, RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED TRIAL
    DUQUETTE, P
    GIRARD, M
    DESPAULT, L
    DUBOIS, R
    KNOBLER, RL
    LUBLIN, FD
    KELLEY, L
    FRANCIS, GS
    LAPIERRE, Y
    ANTEL, J
    FREEDMAN, M
    HUM, S
    GREENSTEIN, JI
    MISHRA, B
    MULDOON, J
    WHITAKER, JN
    EVANS, BK
    LAYTON, B
    SIBLEY, WA
    LAGUNA, J
    KRIKAWA, J
    PATY, DW
    OGER, JJ
    KASTRUKOFF, LF
    MOORE, GRW
    HASHIMOTO, SA
    MORRISON, W
    NELSON, J
    GOODIN, DS
    MASSA, SM
    GUTTERIDGE, E
    ARNASON, BGW
    NORONHA, A
    REDER, AT
    MARTIA, R
    EBERS, GC
    RICE, GPA
    LESAUX, J
    JOHNSON, KP
    PANITCH, HS
    BEVER, CT
    CONWAY, K
    WALLENBERG, JC
    BEDELL, L
    VANDENNOORT, S
    WEINSHENKER, B
    WEISS, W
    REINGOLD, S
    PACHNER, A
    TAYLOR, W
    [J]. NEUROLOGY, 1993, 43 (04) : 655 - 661
  • [2] MULTIPLE-SCLEROSIS IN CHILDHOOD - CLINICAL PROFILE IN 125 PATIENTS
    DUQUETTE, P
    MURRAY, TJ
    PLEINES, J
    EBERS, GC
    SADOVNICK, D
    WELDON, P
    WARREN, S
    PATY, DW
    UPTON, A
    HADER, W
    NELSON, R
    AUTY, A
    NEUFELD, B
    MELTZER, C
    [J]. JOURNAL OF PEDIATRICS, 1987, 111 (03) : 359 - 363
  • [3] Randomised double-blind placebo-controlled study of interferon β-1a in relapsing/remitting multiple sclerosis
    Ebers, GC
    Rice, G
    Lesaux, J
    Paty, D
    Oger, J
    Li, DKB
    Beall, S
    Devonshire, V
    Hashimoto, S
    Hooge, J
    Kastrukoff, L
    Krieger, C
    Mezei, M
    Seland, P
    Vorobeychi, G
    Morrison, W
    Nelson, J
    Freedman, MS
    Chrisie, S
    Nelson, R
    Rabinovitch, H
    Freedman, C
    Hartung, HP
    Rieckmann, P
    Archelos, J
    Jung, S
    Weilbach, F
    Flachenecke, P
    Sauer, J
    Hommes, O
    Jongen, P
    Brouwer, S
    McLeod, J
    Pollard, J
    Ng, R
    Sandberg-Wollheim, M
    Källén, K
    Nilsson, P
    Ekberg, R
    Lundgren, A
    Jadbäck, G
    Wikström, J
    Multanen, J
    Valjakka, M
    Carton, H
    Lissoir, F
    Declerq, I
    Vieren, M
    Peeters, E
    Dubois, B
    [J]. LANCET, 1998, 352 (9139) : 1498 - 1504
  • [4] Multiple sclerosis in childhood: Clinical features of 149 cases
    Ghezzi, A
    Deplano, V
    Faroni, J
    Grasso, MG
    Liguori, M
    Marrosu, G
    Pozzilli, C
    Simone, IL
    Zaffaroni, M
    [J]. MULTIPLE SCLEROSIS, 1997, 3 (01): : 43 - 46
  • [5] Interferon β therapy for multiple sclerosis
    Goodkin, DE
    [J]. LANCET, 1998, 352 (9139) : 1486 - 1487
  • [6] HANEFELD FA, 1994, INT MSJ, V1, P91
  • [7] Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis.
    Jacobs, LD
    Beck, RW
    Simon, JH
    Kinkel, RP
    Brownscheidle, CM
    Murray, TJ
    Simonian, NA
    Slasor, PJ
    Sandrock, AW
    [J]. NEW ENGLAND JOURNAL OF MEDICINE, 2000, 343 (13) : 898 - 904
  • [8] Intramuscular interferon beta-1 alpha for disease progression in relapsing multiple sclerosis
    Jacobs, LD
    Cookfair, DL
    Rudick, RA
    Herndon, RM
    Richert, JR
    Salazar, AM
    Fischer, JS
    Goodkin, DE
    Granger, CV
    Simon, JH
    Alam, JJ
    Bartoszak, DM
    Bourdette, DN
    Braiman, J
    Brownscheidle, CM
    Coats, ME
    Cohan, SL
    Dougherty, DS
    Kinkel, RP
    Mass, MK
    Munschauer, FE
    Priore, RL
    Pullicino, PM
    Scherokman, BJ
    WeinstockGuttman, B
    Whitman, RH
    Baird, WC
    Fillmore, M
    Bona, LM
    ColonRuiz, ME
    Nadine, BS
    Donovan, A
    Bennett, S
    Kieffer, YM
    Umhauer, MA
    Miller, CE
    Kilic, AK
    Sargent, EL
    Schachter, M
    Shucard, DW
    Weider, V
    Catalano, BA
    Cervi, JM
    Czekay, C
    Farrell, JL
    Filippini, JS
    Matyas, RC
    Michienzi, KE
    Ito, M
    OMalley, JA
    [J]. ANNALS OF NEUROLOGY, 1996, 39 (03) : 285 - 294
  • [9] KURTZKE JF, 1983, NEUROLOGY, V33, P1444, DOI 10.1212/WNL.33.11.1444
  • [10] NEW DIAGNOSTIC-CRITERIA FOR MULTIPLE-SCLEROSIS - GUIDELINES FOR RESEARCH PROTOCOLS
    POSER, CM
    PATY, DW
    SCHEINBERG, L
    MCDONALD, WI
    DAVIS, FA
    EBERS, GC
    JOHNSON, KP
    SIBLEY, WA
    SILBERBERG, DH
    TOURTELLOTTE, WW
    [J]. ANNALS OF NEUROLOGY, 1983, 13 (03) : 227 - 231
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