Fragmentation of RGD-peptidomimetics, derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acid, by fast atom bombardment mass spectrometry in positive and negative ion modes

被引：0

作者：

Gren', A. I. ^{[1
]}

Mazepa, A. V. ^{[1
]}

Rakipov, I. M. ^{[1
]}

Ognichenko, L. N. ^{[1
]}

Kuz'min, V. E. ^{[1
]}

机构：

[1] Natl Acad Sci Ukraine, Bogatskii Physicochem Inst, UA-65080 Odessa, Ukraine

来源：

JOURNAL OF ANALYTICAL CHEMISTRY | 2011年 / 66卷 / 13期

关键词：

mass spectrometry; fast atom bombardment; RGD-peptidomimetics; 7-amino-1,2,3,4-tetrahydroisoquinoline; isophthalic acid; fragmentation mechanism; MOBILE;

D O I：

10.1134/S1061934811130041

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

Fragmentation pathways of a series of RGD-peptidomimetics, derivatives of 7-amino-1,2,3,4-tetrahydroisoquinoline and isophthalic acid, were studied by fast atom bombardment mass spectrometry in positive and negative ion modes. Structural factors affecting the formation of fragment ions were determined.

引用

页码：1262 / 1269

页数：8

共 20 条

[11] O'Hair RAJ, 2000, J MASS SPECTROM, V35, P1377, DOI 10.1002/1096-9888(200012)35:12<1377::AID-JMS83>3.0.CO
[12] 2-7
[13] Polce MJ, 2000, J MASS SPECTROM, V35, P1391, DOI 10.1002/1096-9888(200012)35:12<1391::AID-JMS85>3.0.CO
[14] 2-1
[15] Formation of [b(n-1) + OH+H]+ ion structural analogs by solution-phase chemistry
Sharp, JS
Tomer, KB
[J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 2005, 16 (05) : 607 - 621
[16] Takhistov VV., 2005, ORGANICHESKAYA MASS
[17] METASTABLE DECOMPOSITION OF PEPTIDE [M + H]+ IONS VIA REARRANGEMENT INVOLVING LOSS OF THE C-TERMINAL AMINO-ACID RESIDUE
THORNE, GC
BALLARD, KD
GASKELL, SJ
[J]. JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 1990, 1 (03) : 249 - 257
[18] FAST ATOM BOMBARDMENT MASS-SPECTROMETRY - A POWERFUL TECHNIQUE FOR THE STUDY OF POLAR-MOLECULES
WILLIAMS, DH
BRADLEY, C
BOJESEN, G
SANTIKARN, S
TAYLOR, LCE
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1981, 103 (19) : 5700 - 5704
[19] Wysocki VH, 2000, J MASS SPECTROM, V35, P1399, DOI 10.1002/1096-9888(200012)35:12<1399::AID-JMS86>3.0.CO
[20] 2-R

← 1 2 →