Therapeuticall approach of obesity in Prader-Willi syndrome

被引：3
|
作者：
De Carvalho, Daniel F. [1 ]
Cercato, Cintia [1 ]
Almeida, Madson Q. [1 ]
Mancini, Marcio C. [1 ]
Halpern, Alfredo [1 ]
机构：
[1] Univ Sao Paulo, Fac Med, Grp Obesidade & Sindrome Met, Div Endocrinol,Hosp Clin, BR-05508 Sao Paulo, Brazil
来源：
ARQUIVOS BRASILEIROS DE ENDOCRINOLOGIA E METABOLOGIA | 2007年 / 51卷 / 06期
关键词：
obesity; Prader-Willi syndrome; pharmacological treatment; bariatric surgery; topiramate;
D O I：
10.1590/S0004-27302007000600004
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
Prader-Willi Syndrome (PWS) is a multisystemic genetic disease characterized by hypotonia, mental retardation, characteristic facial appearance, hyperphagia, and compulsive eating due to hypothalamic dysfunction. PWS is caused by loss of function of genes located in chromosome 15q11-q13, an area subject to genomic imprinting. Obesity is a major cause of increased morbidity and mortality among patients with PWS. The objective of this study was to analyze the therapeutic options available for the treatment of the obesity in PWS including pharmacological and surgical strategies.
引用
收藏
页码：913 / 919
页数：7
相关论文
共 50 条
  • [41] Anaesthesia and Prader-Willi syndrome
    Dearlove, OR
    Dobson, A
    Super, M
    PAEDIATRIC ANAESTHESIA, 1998, 8 (03): : 267 - 271
  • [42] Prader-Willi syndrome in Taiwan
    Lin, Hsiang-Yu
    Lin, Shuan-Pei
    Yen, Jui-Lung
    Lee, Yann-Jinn
    Huang, Chi-Yu
    Hung, Han-Yang
    Hsu, Chyong-Hsin
    Kao, Hsin-An
    Chang, Jui-Hsing
    Chiu, Nan-Chang
    Ho, Che-Sheng
    Chao, Mei-Chyn
    Niu, Dau-Ming
    Tsai, Li-Ping
    Kuo, Pao-Lin
    PEDIATRICS INTERNATIONAL, 2007, 49 (03) : 375 - 379
  • [43] Prader-Willi syndrome and Angelman syndrome
    Albrecht, B.
    Buiting, K.
    MEDIZINISCHE GENETIK, 2010, 22 (04) : 392 - 398
  • [44] Metabolomic profiling of Prader-Willi syndrome compared with essential obesity
    Rigamonti, Antonello E.
    Polledri, Elisa
    Favero, Chiara
    Caroli, Diana
    Bondesan, Adele
    Grugni, Graziano
    Mai, Stefania
    Cella, Silvano G.
    Fustinoni, Silvia
    Sartorio, Alessandro
    FRONTIERS IN ENDOCRINOLOGY, 2024, 15
  • [45] A multidisciplinary approach to the clinical management of Prader-Willi syndrome
    Duis, Jessica
    van Wattum, Pieter J.
    Scheimann, Ann
    Salehi, Parisa
    Brokamp, Elly
    Fairbrother, Laura
    Childers, Anna
    Shelton, Althea Robinson
    Bingham, Nathan C.
    Shoemaker, Ashley H.
    Miller, Jennifer L.
    MOLECULAR GENETICS & GENOMIC MEDICINE, 2019, 7 (03):
  • [46] Prader-Willi Syndrome and Angelman Syndrome
    Buiting, Karin
    AMERICAN JOURNAL OF MEDICAL GENETICS PART C-SEMINARS IN MEDICAL GENETICS, 2010, 154C (03) : 365 - 376
  • [47] DIET, OBESITY AND ATHEROSCLEROTIC CARDIOVASCULAR RISK IN WILLIAMS SYNDROME, DOWN SYNDROME AND PRADER-WILLI SYNDROME
    Nordstrom, M.
    Paus, B.
    Retterstol, K.
    Andersen, L. F.
    Kolset, S. O.
    JOURNAL OF INTELLECTUAL DISABILITY RESEARCH, 2017, 61 (09) : 823 - 823
  • [48] Hyperphagia and Obesity in Prader-Willi Syndrome: PCSK1 Deficiency and Beyond?
    Ramos-Molina, Bruno
    Molina-Vega, Maria
    Fernandez-Garcia, Jose C.
    Creemers, John W.
    GENES, 2018, 9 (06)
  • [49] Excessive appetitive arousal in Prader-Willi syndrome
    Hinton, E. C.
    Isles, A. R.
    Williams, N. M.
    Parkinson, J. A.
    APPETITE, 2010, 54 (01) : 225 - 228
  • [50] Food Addiction and Cues in Prader-Willi Syndrome
    von Deneen, Karen M.
    Gold, Mark S.
    Liu, Yijun
    JOURNAL OF ADDICTION MEDICINE, 2009, 3 (01) : 19 - 25
12345