A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials

被引:44
作者
Climent, Estela [1 ]
Biyikal, Mustafa [1 ]
Gawlitza, Kornelia [1 ]
Dropa, Tomas [2 ]
Urban, Martin [2 ]
Costero, Ana M. [3 ,4 ,5 ]
Martinez-Manez, Ramon [4 ,5 ,6 ]
Rurack, Knut [1 ]
机构
[1] Bundesanstalt Mat Forsch & Prufung BAM, Chem & Opt Sensing Div 1 9, Richard Willstatter Str 11, D-12489 Berlin, Germany
[2] Natl Inst Nucl Chem & Biol Protect, Lab Tox Cpds, Kamenna 71, Milin 26231, Czech Republic
[3] Univ Valencia, Dept Organ Chem, Dr Moliner 50, E-46100 Valencia, Spain
[4] Univ Valencia, Univ Politecn Valencia, Res Inst Mol Recognit & Technol Dev IDM, Unidad Mixta, E-46003 Valencia, Spain
[5] CIBER Bioingn Biomat & Nanomed CIBER BBN, Madrid, Spain
[6] Univ Politecn Valencia, Dept Chem, Camino de Vera S-N, E-46022 Valencia, Spain
关键词
chemical warfare agents; fluorescence; hybrid sensor materials; nerve gases; test strip analysis; CHEMICAL WARFARE AGENTS; CHROMOGENIC DETECTION; FLUOROGENIC DETECTION; FLUORESCENT SENSORS; DISCRIMINATION; SIMULANTS; DYES;
D O I
10.1002/chem.201601269
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Test strips that in combination with a portable fluorescence reader or digital camera can rapidly and selectively detect chemical warfare agents (CWAs) such as Tabun (GA), Sarin (GB), and Soman (GD) and their simulants in the gas phase have been developed. The strips contain spots of a hybrid indicator material consisting of a fluorescent BODIPY indicator covalently anchored into the channels of mesoporous SBA silica microparticles. The fluorescence quenching response allows the sensitive detection of CWAs in the mu g m(-3) range in a few seconds.
引用
收藏
页码:11138 / 11142
页数:5
相关论文
共 40 条
[11]   Hydroxy Oximes as Organophosphorus Nerve Agent Sensors [J].
Dale, Trevor J. ;
Rebek, Julius, Jr. .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2009, 48 (42) :7850-7852
[12]   Fluorescent Discrimination between Traces of Chemical Warfare Agents and Their Mimics [J].
Diaz de Grenu, Borja ;
Moreno, Daniel ;
Torroba, Tomas ;
Berg, Alexander ;
Gunnars, Johan ;
Nilsson, Tobias ;
Nyman, Rasmus ;
Persson, Milton ;
Pettersson, Johannes ;
Eklind, Ida ;
Wasterby, Par .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2014, 136 (11) :4125-4128
[13]  
Ehrich M., 1998, ENCY TOXICOLOGY, P467
[14]   First supramolecular sensors for phosphonate anions [J].
Esipenko, Nina A. ;
Koutnik, Petr ;
Minami, Tsuyoshi ;
Mosca, Lorenzo ;
Lynch, Vincent M. ;
Zyryanov, Grigory V. ;
Anzenbacher, Pavel, Jr. .
CHEMICAL SCIENCE, 2013, 4 (09) :3617-3623
[15]  
Everts S, 2015, CHEM ENG NEWS, V93, P10
[16]   Rapid 'naked eye' response of DCP, a nerve agent simulant: from molecules to low-cost devices for both liquid and vapour phase detection [J].
Goswami, Shyamaprosad ;
Manna, Abhishek ;
Paul, Sima .
RSC ADVANCES, 2014, 4 (42) :21984-21988
[17]   Detection of nerve agent stimulants based on photoluminescent porous silicon interferometer [J].
Kim, Seongwoong ;
Cho, Bomin ;
Sohn, Honglae .
NANOSCALE RESEARCH LETTERS, 2012, 7 :1-6
[18]  
Knapton D., 2006, ANGEW CHEM, V118, P5957, DOI [10.1002/ange.200601634, DOI 10.1002/ANGE.200601634]
[19]   Fluorescent organometallic sensors for the detection of chemical-warfare-agent mimics [J].
Knapton, Daniel ;
Burnworth, Mark ;
Rowan, Stuart J. ;
Weder, Christoph .
ANGEWANDTE CHEMIE-INTERNATIONAL EDITION, 2006, 45 (35) :5825-5829
[20]   Chromogenic and fluorogenic detection and discrimination of nerve agents Tabun and Vx [J].
Kumar, Vinod ;
Rana, Hemlata .
CHEMICAL COMMUNICATIONS, 2015, 51 (92) :16490-16493