A Rapid and Sensitive Strip-Based Quick Test for Nerve Agents Tabun, Sarin, and Soman Using BODIPY-Modified Silica Materials

被引:44
作者
Climent, Estela [1 ]
Biyikal, Mustafa [1 ]
Gawlitza, Kornelia [1 ]
Dropa, Tomas [2 ]
Urban, Martin [2 ]
Costero, Ana M. [3 ,4 ,5 ]
Martinez-Manez, Ramon [4 ,5 ,6 ]
Rurack, Knut [1 ]
机构
[1] Bundesanstalt Mat Forsch & Prufung BAM, Chem & Opt Sensing Div 1 9, Richard Willstatter Str 11, D-12489 Berlin, Germany
[2] Natl Inst Nucl Chem & Biol Protect, Lab Tox Cpds, Kamenna 71, Milin 26231, Czech Republic
[3] Univ Valencia, Dept Organ Chem, Dr Moliner 50, E-46100 Valencia, Spain
[4] Univ Valencia, Univ Politecn Valencia, Res Inst Mol Recognit & Technol Dev IDM, Unidad Mixta, E-46003 Valencia, Spain
[5] CIBER Bioingn Biomat & Nanomed CIBER BBN, Madrid, Spain
[6] Univ Politecn Valencia, Dept Chem, Camino de Vera S-N, E-46022 Valencia, Spain
关键词
chemical warfare agents; fluorescence; hybrid sensor materials; nerve gases; test strip analysis; CHEMICAL WARFARE AGENTS; CHROMOGENIC DETECTION; FLUOROGENIC DETECTION; FLUORESCENT SENSORS; DISCRIMINATION; SIMULANTS; DYES;
D O I
10.1002/chem.201601269
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Test strips that in combination with a portable fluorescence reader or digital camera can rapidly and selectively detect chemical warfare agents (CWAs) such as Tabun (GA), Sarin (GB), and Soman (GD) and their simulants in the gas phase have been developed. The strips contain spots of a hybrid indicator material consisting of a fluorescent BODIPY indicator covalently anchored into the channels of mesoporous SBA silica microparticles. The fluorescence quenching response allows the sensitive detection of CWAs in the mu g m(-3) range in a few seconds.
引用
收藏
页码:11138 / 11142
页数:5
相关论文
共 40 条
[1]  
[Anonymous], 1998, CONF MAN PERF VER EX, P60
[2]  
[Anonymous], 1995, NERV AG MED MAN CHEM
[3]  
[Anonymous], 2012, M8 DEP ARM, P7
[4]   Highly Selective Detection of Nerve-Agent Simulants with BODIPY Dyes [J].
Barba-Bon, Andrea ;
Costero, Ana M. ;
Gil, Salvador ;
Harriman, Anthony ;
Sancenon, Felix .
CHEMISTRY-A EUROPEAN JOURNAL, 2014, 20 (21) :6339-6347
[5]   Colorimetric Stimuli-Responsive Hydrogel Polymers for the Detection of Nerve Agent Surrogates [J].
Belger, Christian ;
Weis, Jonathan G. ;
Egap, Eilaf ;
Swager, Timothy M. .
MACROMOLECULES, 2015, 48 (21) :7990-7994
[6]   Microbead chemical switches: An approach to detection of reactive organophosphate chemical warfare agent vapors [J].
Bencic-Nagale, S ;
Sternfeld, T ;
Walt, DR .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (15) :5041-5048
[7]   Fluorescent Sensors for the Detection of Chemical Warfare Agents [J].
Burnworth, Mark ;
Rowan, Stuart J. ;
Weder, Christoph .
CHEMISTRY-A EUROPEAN JOURNAL, 2007, 13 (28) :7828-7836
[8]   Chromogenic detection of nerve agent mimics [J].
Costero, Ana M. ;
Gil, Salvador ;
Parra, Margarita ;
Mancini, Pedro M. E. ;
Martinez-Manez, Ramon ;
Sancenon, Felix ;
Royo, Santiago .
CHEMICAL COMMUNICATIONS, 2008, (45) :6002-6004
[9]  
Dale T. J., 2009, ANGEW CHEM, V121, P7990, DOI DOI 10.1002/ANGE.200902820
[10]   Fluorescent sensors for organophosphorus nerve agent mimics [J].
Dale, TJ ;
Rebek, J .
JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2006, 128 (14) :4500-4501