Infliximab for ulcerative colitis following liver transplantation

被引：31

作者：

Lal, Simon ^{[2
]}

Steinhart, A. Hillary ^{[1
]}

机构：

[1] Mt Sinai Hosp, Div Gastroenterol, Inflammatory Bowel Dis Ctr, Toronto, ON M5G 1X5, Canada

[2] Univ Hosp, Dept Gastroenterol, Liverpool, Merseyside, England

来源：

EUROPEAN JOURNAL OF GASTROENTEROLOGY & HEPATOLOGY | 2007年 / 19卷 / 03期

关键词：

infliximab; liver transplantation; primary sclerosing cholangitis; ulcerative colitis;

D O I：

10.1097/MEG.0b013e3280116ccc

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Primary sclerosing cholangitis is a chronic cholestatic disease with a progressive course, often culminating in hepatic transplantation. When associated with primary sclerosing cholangitis, ulcerative colitis commonly follows a mild course before, but a more progressive course following liver transplantation, with a significant proportion of patients becoming steroid dependent and/or requiring colectomy. We report the first case demonstrating the efficacy and safety of infliximab therapy for ulcerative colitis following hepatic transplantation. Eur J Gastroenterol Hepatol 19:277-280 (C) 2007 Lippincott Williams & Wilkins.

引用

页码：277 / 280

页数：4

共 26 条

[1] Tacrolimus is safe and effective in patients with severe steroid-refractory or steroid-dependent inflammatory bowel disease - A long-term follow-up [J].

Baumgart, Daniel C. ;

Pintoffl, Jan P. ;

Sturm, Andreas ;

Wiedenmann, Bertram ;

Dignass, Axel U. .

AMERICAN JOURNAL OF GASTROENTEROLOGY, 2006, 101 (05) :1048-1056

[2] Clinical course and management of inflammatory bowel disease after liver transplantation [J].

Befeler, AS ;

Lissoos, TW ;

Schiano, TD ;

Conjeevaram, H ;

Dasgupta, KA ;

Millis, JM ;

Newell, KA ;

Thistlethwaite, JR ;

Baker, AL .

TRANSPLANTATION, 1998, 65 (03) :393-396

[3] INCREASED RISK OF EARLY COLORECTAL NEOPLASMS AFTER HEPATIC TRANSPLANT IN PATIENTS WITH INFLAMMATORY BOWEL-DISEASE [J].

BLEDAY, R ;

LEE, E ;

JESSURUN, J ;

HEINE, J ;

WONG, WD .

DISEASES OF THE COLON & RECTUM, 1993, 36 (10) :908-912

[4]

BUSUTTIL RW, 1994, NEW ENGL J MED, V331, P1110

[5] The colon and PSC: new liver, new danger? [J].

Chapman, RW .

GUT, 1998, 43 (05) :595-596

[6] PRIMARY SCLEROSING CHOLANGITIS - A REVIEW OF ITS CLINICAL-FEATURES, CHOLANGIOGRAPHY, AND HEPATIC HISTOLOGY [J].

CHAPMAN, RWG ;

ARBORGH, BAM ;

RHODES, JM ;

SUMMERFIELD, JA ;

DICK, R ;

SCHEUER, PJ ;

SHERLOCK, S .

GUT, 1980, 21 (10) :870-877

[7] The safety profile of infliximab in patients with Crohn's disease: The Mayo Clinic experience in 500 patients [J].

Colombel, JF ;

Loftus, EV ;

Tremaine, WJ ;

Egan, LJ ;

Harmsen, WS ;

Schleck, CD ;

Zinsmeister, AR ;

Sandborn, WJ .

GASTROENTEROLOGY, 2004, 126 (01) :19-31

[8] Severe acute colitis associated with CMV:: a prevalence study [J].

Criscuoli, V ;

Casà, A ;

Orlando, A ;

Pecoraro, G ;

Oliva, L ;

Traina, M ;

Rizzo, A ;

Cottone, M .

DIGESTIVE AND LIVER DISEASE, 2004, 36 (12) :818-820

[9] Guidelines for screening and surveillance of asymptomatic colorectal cancer in patients with inflammatory bowel disease [J].

Eaden, JA ;

Mayberry, JF .

GUT, 2002, 51 :V10-V12

[10] ULCERATIVE-COLITIS DISEASE-ACTIVITY AS SUBJECTIVELY ASSESSED BY PATIENT-COMPLETED QUESTIONNAIRES FOLLOWING ORTHOTOPIC LIVER-TRANSPLANTATION FOR SCLEROSING CHOLANGITIS [J].

GAVALER, JS ;

DELEMOS, B ;

BELLE, SH ;

HEYL, AE ;

TARTER, RE ;

STARZL, TE ;

GAVALER, C ;

VANTHIEL, DH .

DIGESTIVE DISEASES AND SCIENCES, 1991, 36 (03) :321-328

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