Assessment of the compliance, influencing factors, and yielding results of liver cancer screening in a high-risk population: A cross-sectional study

被引：4

作者：

Cao, Maomao ^{[1
]}

Li, He ^{[1
]}

Sun, Dianqin ^{[1
]}

He, Siyi ^{[1
]}

Yang, Fan ^{[1
]}

Yan, Xinxin ^{[1
]}

Zhang, Shaoli ^{[1
]}

Zha, Zhenqiu ^{[2
]}

Zhou, Jinyi ^{[3
]}

Luo, Pengfei ^{[3
]}

Gong, Jiyong ^{[4
,5
]}

Ma, Hengmin ^{[4
,5
]}

Zhang, Shaokai ^{[6
,7
]}

Sun, Xibin ^{[6
,7
]}

Xia, Changfa ^{[1
]}

Peng, Ji ^{[8
]}

Chen, Wanqing ^{[1
]}

机构：

[1] Chinese Acad Med Sci & Peking Union Med Coll, Chinese Acad Med Sci, Canc Hosp,Key Lab Natl Canc Big Data Anal & Imple, Off Canc Screening,Natl Canc Ctr,Natl Clin Res Ct, Beijing 100021, Peoples R China

[2] Anhui Prov Ctr Dis Control & Prevent, Inst Chron Noncommunicable Dis Prevent & Control, Hefei, Peoples R China

[3] Publ Hlth Res Inst Jiangsu Prov, Jiangsu Prov Ctr Dis Control & Prevent, Dept Chron Noncommunicable Dis Control, Nanjing, Peoples R China

[4] Shandong First Med Univ, Shandong Canc Hosp & Inst, Dept Prevent Management, Jinan, Peoples R China

[5] Shandong Acad Med Sci, Jinan, Peoples R China

[6] Zhengzhou Univ, Affiliated Canc Hosp, Dept Dis Prevent, Zhengzhou, Peoples R China

[7] Henan Canc Hosp, Zhengzhou, Peoples R China

[8] Shenzhen Ctr Chron Dis Control, Dept Canc Prevent & Control, Shenzhen 518020, Peoples R China

来源：

CANCER | 2022年 / 128卷 / 20期

基金：

中国国家自然科学基金;

关键词：

early detection; liver cancer; participation rate; risk factors; screening; RANDOMIZED CONTROLLED-TRIAL; HEPATOCELLULAR-CARCINOMA; IMPROVES SURVIVAL; SURVEILLANCE; MANAGEMENT; DIAGNOSIS;

D O I：

10.1002/cncr.34418

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Background The participation and results for liver cancer screening are rarely reported. The aim of this study was to determine the participation rates and factors affecting participation rates as well as to report the detection rate for liver cancer in an organized screening program. Methods The organized screening program for liver cancer was conducted in 12 rural sites. The risk of developing liver cancer was initially evaluated for each participant. High-risk individuals were offered alpha-fetoprotein measurement and ultrasonography examination. Potential risk factors associated with the participation rate were screened by fitted generalized linear mixed logistic regression models through reporting odds ratios (ORs) with 95% CIs. Results A total of 358,662 eligible participants completed the basic surveys, and 54,745 were evaluated to be at high risk of liver cancer. Of these high-risk individuals, 40,543 accepted the screening services. Determinants of participation for screening behavior included older age, being female, being positive for hepatitis B surface antigen, having a family history of liver cancer, chronic depression, and low income. The detection rate for liver cancer was estimated to be 0.41% (95% CI, 0.35-0.48). Conclusions This study reported several significant factors associated with the screening behaviors for liver cancer. Lay Summary Participation rate and results for liver cancer screening in rural areas are rarely reported. The determinants associated with adherence rates and early detection rate of liver cancer in an organized screening program for liver cancer were assessed. A possible positive correlation between the participation rates and the early detection rate was observed among attendees of screening. These new finds could be beneficial to increasing the participation rate of screening.

引用

页码：3653 / 3662

页数：10

共 29 条

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