Algorithm for the diagnosis and treatment of pediatric OSA: A proposal of two pediatric sleep centers

被引:98
作者
Kaditis, Athanasios [1 ,2 ]
Kheirandish-Gozal, Leila [3 ]
Gozal, David [3 ]
机构
[1] Aghia Sophia Childrens Hosp, Univ Dept Pediat 1, Athens 11527, Greece
[2] Univ Athens, Sch Med, Univ Dept Pediat 1, Pediat Pulmonol Unit,Sleep Disorders Lab, GR-11527 Athens, Greece
[3] Univ Chicago, Pritzker Sch Med, Dept Pediat, Sect Pediat Sleep Med, Chicago, IL 60637 USA
关键词
Adenotonsillar hypertrophy; Craniofacial abnormalities; Obesity; Obstructive sleep apnea; Snoring; neuromuscular disorders; UPPER AIRWAY-OBSTRUCTION; THE TUCSON CHILDRENS; QUALITY-OF-LIFE; NATRIURETIC PEPTIDE LEVELS; RAPID MAXILLARY EXPANSION; AMBULATORY BLOOD-PRESSURE; C-REACTIVE PROTEIN; FAILURE-TO-THRIVE; LONG-TERM CHANGES; APNEA SYNDROME;
D O I
10.1016/j.sleep.2011.09.009
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
There is currently no consensus on the best method of managing of obstructive sleep apnea (USA) in childhood. In the present paper, an algorithm for the diagnosis and treatment of the disorder is proposed. Sleep apnea is suspected when parents report relevant symptoms or when there are abnormalities that predispose to USA such as adenotonsillar hypertrophy, obesity, craniofacial anomalies, or neuromuscular disorders. USA-associated morbidity including elevated blood pressure, daytime sleepiness or learning problems, growth failure, and enuresis should be recognized. Severity of intermittent upper airway obstruction during sleep can be determined objectively by polysomnography or, if polysomnography is not available, by nocturnal pulse oximetry. Risk factors predicting persistence of USA in adolescence (male gender, development of obesity) need to be identified. Children with moderate-to-severe USA, or with mild USA, but accompanied by morbidity, or by risk factors predicting persistence of the disorder should have priority for treatment. An individualized and multifaceted therapeutic approach which addresses in a step-by-step fashion all abnormalities that contribute to upper airway obstruction during sleep is necessary. (C) 2011 Elsevier B.V. All rights reserved.
引用
收藏
页码:217 / 227
页数:11
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