The main pigment of the dormant Mycobacterium smegmatis is porphyrin

被引：23

作者：

Nikitushkin, V. D. ^{[1
]}

Shleeva, M. O. ^{[1
]}

Zinin, A. I. ^{[2
]}

Trutneva, K. A. ^{[1
]}

Ostrovsky, D. N. ^{[1
]}

Kaprelyants, A. S. ^{[1
]}

机构：

[1] Russian Acad Sci, Fed Res Ctr Fundamentals Biotechnol, AN Bach Inst Biochem, Leninsky Pr 33,Bldg 2, Moscow 119071, Russia

[2] Russian Acad Sci, Zelinsky Inst Organ Chem, Leninsky Pr 47, Moscow 119991, Russia

来源：

FEMS MICROBIOLOGY LETTERS | 2016年 / 363卷 / 19期

基金：

俄罗斯科学基金会;

关键词：

Mycobacteria; Mycobacterium smegmatis; dormancy; pigmentation; porphyrins; MALDI; SPECTRA;

D O I：

10.1093/femsle/fnw206

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

Upon transition of Mycobacterium smegmatis into the dormant state, accumulation of a dark brown fluorescent pigment was observed. This pigment gave bright red fluorescence in both cells and the culture medium. Based on H-1-NMR, MALDI and UV spectra, the fluorescent compounds, extracted from the culture medium as well as from the dormant cells, were concluded to be a mixture of free coproporphyrin III and uroporphyrin III and their corresponding methyl esters. A possible significance of porphyrin pigment accumulation in the dormant cells is discussed.

引用

页数：8

共 19 条

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