Bioactive constituents from roots of Bursera tonkinensis

被引:145
作者
Jutiviboonsuk, A
Zhang, HJ
Tan, GT
Ma, CY
Van Hung, N
Cuong, NM
Bunyapraphatsara, N
Soejarto, DD
Fong, HHS
机构
[1] Mahidol Univ, Fac Pharm, Dept Pharmacognosy, Bangkok 10400, Thailand
[2] Univ Illinois, Coll Pharm, Dept Med Chem & Pharmacognosy, Program Collaborat Res Pharmaceut Sci, Chicago, IL 60612 USA
[3] Vietanamese Acad Sci & Technol, Inst Chem, Cau Giay, Vietnam
关键词
Bursera tonkinensis; Burseraceae; cytotoxicity; burselignan; burseneolignan; bursephenylpropane;
D O I
10.1016/j.phytochem.2005.09.025
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Bioassay directed-fractionation led to isolation of 12 compounds from the roots of Bursera tonkinensis Guillaum (Burseraceae), including burselignan, bursephenylpropane, and burseneolignan. Of the 12 compounds, only 4'-demethyldesoxypodophyllotoxin exhibited significant cytotoxic activities against KB, Col2 and LNCaP cell lilies. (c) 2005 Elsevier Ltd. All rights reserved.
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页码:2745 / 2751
页数:7
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