Monitoring and Diagnostic Approaches for Pulmonary Arterial Hypertension in Patients with Systemic Sclerosis

被引：12

作者：

Valenzuela, Antonia ^{[1
]}

Nandagopal, Saranya ^{[2
]}

Steen, Virginia D. ^{[3
]}

Chung, Lorinda ^{[1
]}

机构：

[1] Stanford Univ, Sch Med, Dept Immunol & Rheumatol, Palo Alto, CA 94304 USA

[2] Stanford Univ, Sch Med, Dept Dermatol, Redwood City, CA 94063 USA

[3] Georgetown Univ, Sch Med, Div Rheumatol Allergy & Immunol, Pasquerilla Hlth Ctr, Washington, DC 20007 USA

来源：

RHEUMATIC DISEASE CLINICS OF NORTH AMERICA | 2015年 / 41卷 / 03期

关键词：

Systemic sclerosis; Pulmonary arterial hypertension; Monitoring; Diagnosis; BRAIN NATRIURETIC PEPTIDE; ANTIENDOTHELIAL CELL ANTIBODIES; 6-MINUTE WALK TEST; VENOOCCLUSIVE DISEASE; LUNG TRANSPLANTATION; SCLERODERMA SPECTRUM; SCREENING ALGORITHM; DIFFUSING-CAPACITY; ORAL TREPROSTINIL; SYSTOLIC PRESSURE;

D O I：

10.1016/j.rdc.2015.04.009

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Pulmonary arterial hypertension (PAH) is one of the leading causes of death in patients with systemic sclerosis (SSc). Given the high prevalence and poor survival of SSc-PAH, and that aggressive management of mild disease may be associated with better outcomes, screening is critical. Right heart catheterization (RHO) is the gold standard for the definitive diagnosis of PAH, and should be performed in those patients in whom this diagnosis is suspected. Once a diagnosis of PAH is confirmed by RHO, treatment with PAH-specific therapies should be initiated as soon as possible.

引用

页码：489 / +

页数：19

共 100 条

[1] Anti-U3 RNP Autoantibodies in Systemic Sclerosis [J].

Aggarwal, Rohit ;

Lucas, Mary ;

Fertig, Noreen ;

Oddis, Chester V. ;

Medsger, Thomas A., Jr. .

ARTHRITIS AND RHEUMATISM, 2009, 60 (04) :1112-1118

[2] High N-terminal pro-brain natriuretic peptide levels and low diffusing capacity for carbon monoxide as independent predictors of the occurrence of precapillary pulmonary arterial hypertension in patients with systemic sclerosis [J].

Allanore, Y. ;

Avouac, J. ;

Zerkak, D. ;

Meune, C. ;

Hachulla, E. ;

Mouthon, L. ;

Guillevin, L. ;

Meyer, O. ;

Ekindjian, O. G. ;

Weber, S. ;

Kahan, A. .

ARTHRITIS AND RHEUMATISM, 2008, 58 (01) :284-291

[3]

[Anonymous], ARTHRITIS RHEUM

[4]

Assous N, 2005, CLIN EXP RHEUMATOL, V23, P199

[5] Prevalence of Pulmonary Hypertension in Systemic Sclerosis in European Caucasians and Metaanalysis of 5 Studies [J].

Avouac, Jerome ;

Airo, Paulo ;

Meune, Christophe ;

Beretta, Lorenzo ;

Dieude, Philippe ;

Caramaschi, Paola ;

Tiev, Kiet ;

Cappelli, Susanna ;

Diot, Elisabeth ;

Vacca, Alessandra ;

Cracowski, Jean-Luc ;

Sibilia, Jean ;

Kahan, Andre ;

Matucci-Cerinic, Marco ;

Allanore, Yannick .

JOURNAL OF RHEUMATOLOGY, 2010, 37 (11) :2290-2298

[6]

Badesch DB, 2007, J RHEUMATOL, V34, P2417

[7] Longterm Survival Among Patients with Scleroderma-associated Pulmonary Arterial Hypertension Treated with Intravenous Epoprostenol [J].

Badesch, David B. ;

McGoon, Michael D. ;

Barst, Robin J. ;

Tapson, Victor F. ;

Rubin, Lewis J. ;

Wigley, Fredrick M. ;

Kral, Kenneth M. ;

Raphiou, Ibrahim H. ;

Crater, Glenn D. .

JOURNAL OF RHEUMATOLOGY, 2009, 36 (10) :2244-2249

[8] Diagnosis and Assessment of Pulmonary Arterial Hypertension [J].

Badesch, David B. ;

Champion, Hunter C. ;

Gomez Sanchez, Miguel Angel ;

Hoeper, Marius M. ;

Loyd, James E. ;

Manes, Alessandra ;

McGoon, Michael ;

Naeije, Robert ;

Olschewski, Horst ;

Oudiz, Ronald J. ;

Torbicki, Adam .

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2009, 54 (01) :S55-S66

[9] Continuous intravenous epoprostenol for pulmonary hypertension due to the scleroderma spectrum of disease -: A randomized, controlled trial [J].

Badesch, DB ;

Tapson, VF ;

McGoon, MD ;

Brundage, BH ;

Rubin, LJ ;

Wigley, FM ;

Rich, S ;

Barst, RJ ;

Barrett, PS ;

Kral, KM ;

Jöbsis, MM ;

Loyd, JE ;

Murali, S ;

Frost, A ;

Girgis, R ;

Bourge, RC ;

Ralph, DD ;

Elliott, CG ;

Hill, NS ;

Langleben, D ;

Schilz, RJ ;

McLaughlin, VV ;

Robbins, IM ;

Groves, BM ;

Shapiro, S ;

Medsger, TA ;

Gaine, SP ;

Horn, E ;

Decker, JC ;

Knobil, K .

ANNALS OF INTERNAL MEDICINE, 2000, 132 (06) :425-+

[10] Baseline characteristics and follow-up in patients with normal haemodynamics versus borderline mean pulmonary arterial pressure in systemic sclerosis: results from the PHAROS registry [J].

Bae, Sangmee ;

Saggar, Rajeev ;

Bolster, Marcy B. ;

Chung, Lorinda ;

Csuka, Mary Ellen ;

Derk, Chris ;

Domsic, Robyn ;

Fischer, Aryeh ;

Frech, Tracy ;

Goldberg, Avram ;

Hinchcliff, Monique ;

Hsu, Vivien ;

Hummers, Laura ;

Schiopu, Elena ;

Mayes, Maureen D. ;

McLaughlin, Vallerie ;

Molitor, Jerry ;

Naz, Nausheen ;

Furst, Daniel E. ;

Maranian, Paul ;

Steen, Virginia ;

Khanna, Dinesh .

ANNALS OF THE RHEUMATIC DISEASES, 2012, 71 (08) :1335-1342

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