Messenger RNA Modifications in Plants

被引：91
作者：
Shen, Lisha [1 ]
Liang, Zhe [2 ]
Wong, Chui Eng [1 ,2 ]
Yu, Hao [1 ,2 ]
机构：
[1] Natl Univ Singapore, Temasek Life Sci Lab, 1 Res Link, Singapore 117604, Singapore
[2] Natl Univ Singapore, Dept Biol Sci, 14 Sci Dr 4, Singapore 117543, Singapore
来源：
TRENDS IN PLANT SCIENCE | 2019年 / 24卷 / 04期
基金：
新加坡国家研究基金会;
关键词：
SINGLE-NUCLEOTIDE-RESOLUTION; MAPPING REVEALS; NUCLEAR-RNA; N-6-METHYLADENOSINE RNA; GENE-EXPRESSION; YTH DOMAIN; METHYLATION; ARABIDOPSIS; URIDYLATION; 5-METHYLCYTOSINE;
D O I：
10.1016/j.tplants.2019.01.005
中图分类号：
Q94 [植物学];
学科分类号：
071001 ;
摘要：
Over 160 distinct RNA modifications are known and collectively termed the epitranscriptome. Some of these modifications have been discovered in mRNA, uncovering a new layer of gene regulation. Transcriptome-wide mapping of epitranscriptomic codes and the discovery of their writers, erasers, and readers that dynamically install, remove, and interpret RNA modifications, respectively, are fundamental to understanding the epitranscriptome. Recent technologies have enabled the transcriptome-wide profiling of several mRNA modifications in Arabidopsis thaliana, providing key insights into regulating these modifications and their effects on plant development. Here we review technological innovations and recent progress in epitranscriptomics, with specific focus on N-6-methyladenosine (m(6)A), 5-methylcytosine (m(5)C), uridylation, and their roles in multiple aspects of plant development.
引用
收藏
页码：328 / 341
页数：14
相关论文
共 99 条
  • [1] HNRNPA2B1 Is a Mediator of m6A-Dependent Nuclear RNA Processing Events
    Alarcon, Claudio R.
    Goodarzi, Hani
    Lee, Hyeseung
    Liu, Xuhang
    Tavazoie, Saeed
    Tavazoie, Sohail F.
    [J]. CELL, 2015, 162 (06) : 1299 - 1308
  • [2] Distinct 5-methylcytosine profiles in poly(A) RNA from mouse embryonic stem cells and brain
    Amort, Thomas
    Rieder, Dietmar
    Wille, Alexandra
    Khokhlova-Cubberley, Daria
    Riml, Christian
    Trixl, Lukas
    Jia, Xi-Yu
    Micura, Ronald
    Lusser, Alexandra
    [J]. GENOME BIOLOGY, 2017, 18
  • [3] An m6A-YTH Module Controls Developmental Timing and Morphogenesis in Arabidopsis[OPEN]
    Arribas-Hernandez, Laura
    Bressendorff, Simon
    Hansen, Mathias Henning
    Poulsen, Christian
    Erdmann, Susanne
    Brodersen, Peter
    [J]. PLANT CELL, 2018, 30 (05) : 952 - 967
  • [4] TLC-based detection of methylated cytosine: application to aging epigenetics
    Barciszewska, Miroslawa Z.
    Barciszewska, Anna Maria
    Rattan, Suresh I. S.
    [J]. BIOGERONTOLOGY, 2007, 8 (06) : 673 - 678
  • [5] Adenosine methylation in Arabidopsis mRNA is associated with the 3′ end and reduced levels cause developmental defects
    Bodi, Zsuzsanna
    Zhong, Silin
    Mehra, Surbhi
    Song, Jie
    Graham, Neil
    Li, Hongying
    May, Sean
    Fray, Rupert George
    [J]. FRONTIERS IN PLANT SCIENCE, 2012, 3
  • [6] Bokar JA, 1997, RNA, V3, P1233
  • [7] Deciphering the epitranscriptome: A green perspective
    Burgess, Alice
    David, Rakesh
    Searle, Iain Robert
    [J]. JOURNAL OF INTEGRATIVE PLANT BIOLOGY, 2016, 58 (10) : 822 - 835
  • [8] Conservation of tRNA and rRNA 5-methylcytosine in the kingdom Plantae
    Burgess, Alice Louise
    David, Rakesh
    Searle, Iain Robert
    [J]. BMC PLANT BIOLOGY, 2015, 15
  • [9] Pseudouridine profiling reveals regulated mRNA pseudouridylation in yeast and human cells
    Carlile, Thomas M.
    Rojas-Duran, Maria F.
    Zinshteyn, Boris
    Shin, Hakyung
    Bartoli, Kristen M.
    Gilbert, Wendy V.
    [J]. NATURE, 2014, 515 (7525) : 143 - +
  • [10] TAIL-seq: Genome-wide Determination of Poly(A) Tail Length and 3′ End Modifications
    Chang, Hyeshik
    Lim, Jaechul
    Ha, Minju
    Kim, V. Narry
    [J]. MOLECULAR CELL, 2014, 53 (06) : 1044 - 1052
12345678910