Optimizing immobilization, margins, and imaging for lung stereotactic body radiation therapy

被引：18

作者：

Molitoris, Jason K. ^{[1
]}

Diwanji, Tejan ^{[2
]}

Snider, James W., III ^{[1
]}

Mossahebi, Sina ^{[1
]}

Samanta, Santanu ^{[2
]}

Onyeuku, Nasarachi ^{[2
]}

Mohindra, Pranshu ^{[1
]}

Choi, J. Isabelle ^{[1
]}

Simone, Charles B., II ^{[1
]}

机构：

[1] Univ Maryland, Sch Med, Dept Radiat Oncol, 22 S Greene St,GGJ 35, Baltimore, MD 21201 USA

[2] Univ Maryland, Med Ctr, Dept Radiat Oncol, Baltimore, MD 21201 USA

来源：

TRANSLATIONAL LUNG CANCER RESEARCH | 2019年 / 8卷 / 01期

关键词：

Radiation; non-small cell lung cancer (NSCLC); motion management; image guidance; margins; 4-DIMENSIONAL COMPUTED-TOMOGRAPHY; CONE-BEAM CT; HIGH-DOSE IRRADIATION; REAL-TIME TUMOR; RESPIRATORY MOTION; ABDOMINAL COMPRESSION; PHASE-II; RADIOTHERAPY; CANCER; REGISTRATION;

D O I：

10.21037/tlcr.2018.09.25

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

The simultaneous advancement of technologies for the delivery of precisely targeted radiation therapy and the paradigm shift to substantial hypofractionation have led to significant improvements in the treatment of early stage non-small cell lung cancer (ES-NSCLC). Stereotactic body radiation therapy (SBRT) has become a well-established option for the treatment of ES-NSCLC and is now becoming widely available within the radiation oncology community. Implementation of this technique, however, requires highly accurate target delineation, thorough evaluation of tumor motion, and improved on-board imaging at the time of treatment for patient alignment, each of which is critical for successful tumor control and mitigation of risks to normal tissues. In this article, we review updates and issues related to immobilization and image guidance for SBRT in the treatment of ES-NSCLC.

引用

页码：24 / 31

页数：8

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